Structure and Function of the Bestrophin family of calcium-activated chloride channels

Bestrophins are a family of calcium-activated chloride channels (CaCCs) with relevance to human physiology and a myriad of eye diseases termed "bestrophinopathies". Since the identification of bestrophins as CaCCs nearly two decades ago, extensive studies from electrophysiological and stru...

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Veröffentlicht in:	Channels (Austin, Tex.) Tex.), 2021-01, Vol.15 (1), p.604-623
Hauptverfasser:	Owji, Aaron P., Kittredge, Alec, Zhang, Yu, Yang, Tingting
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Best1 Best2 Bestrophin function Bestrophin structure Bestrophins Calcium - metabolism Cattle Chloride Channels Crystallography, X-Ray Electrophysiological Phenomena Eye Proteins - metabolism Humans Review Reviews
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