Predictors of Virological Failure and Time to Viral Suppression of First-Line Integrase Inhibitor–Based Antiretroviral Treatment

BACKGROUNDIntegrase strand transfer inhibitors (InSTIs) are recommended for first-line treatment of persons with human immunodeficiency virus (HIV). We identified risk factors, including baseline minor InSTI resistance mutations, for treatment failure of InSTI-based regimens. METHODSWe studied time-...

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Veröffentlicht in:	Clinical infectious diseases 2021-10, Vol.73 (7), p.e2134-e2141
Hauptverfasser:	Pyngottu, Ashima, Scherrer, Alexandra U, Kouyos, Roger, Huber, Michael, Hirsch, Hans, Perreau, Matthieu, Yerly, Sabine, Calmy, Alexandra, Cavassini, Matthias, Stöckle, Marcel, Furrer, Hansjakob, Vernazza, Pietro, Bernasconi, Enos, Günthard, Huldrych F, Aebi-Popp, K, Anagnostopoulos, A, Battegay, M, Bernasconi, E, Böni, J, Braun, D L, Bucher, H C, Calmy, A, Cavassini, M, Ciuffi, A, Dollenmaier, G, Egger, M, Elzi, L, Fehr, J, Fellay, J, Furrer, H, Fux, C A, Günthard, H F, Haerry, D, Hasse, B, Hirsch, H H, Hoffmann, M, Hösli, I, Huber, M, Kahlert, C R, Kaiser, L, Keiser, O, Klimkait, T, Kouyos, R D, Kovari, H, Ledergerber, B, Martinetti, G, Martinez de Tejada, B, Marzolini, C, Metzner, K J, Müller, N, Nicca, D, Paioni, P, Pantaleo, G, Perreau, M, Rauch, A, Rudin, C, Scherrer, A U, Schmid, P, Speck, R, Stöckle, M, Tarr, P, Trkola, A, Vernazza, P, Wandeler, G, Weber, R, Yerly, S
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Sprache:	eng
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