Catalytic Diastereo- and Enantioselective Vinylogous Mannich Reaction of Alkylidenepyrazolones to Isatin-Derived Ketimines

A valuable organocatalytic vinylogous Mannich reaction between alkylidenepyrazolones and isatin-derived ketimines has been successfully established. Squaramide organocatalyst, prepared from quinine, catalyzed the diastereo- and enantioselective vinylogous Mannich addition, affording a range of amino...

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Veröffentlicht in:	Organic letters 2021-10, Vol.23 (19), p.7391-7395
Hauptverfasser:	Carceller-Ferrer, Laura, Vila, Carlos, Blay, Gonzalo, Muñoz, M. Carmen, Pedro, José R
Format:	Artikel
Sprache:	eng
Schlagworte:	Letter
Online-Zugang:	Volltext
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