Clinicopathologic and Genomic Landscape of Breast Carcinoma Brain Metastases

Background Among patients with breast carcinoma who have metastatic disease, 15%–30% will eventually develop brain metastases. We examined the genomic landscape of a large cohort of patients with breast carcinoma brain metastases (BCBMs) and compared it with a cohort of patients with primary breast...

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Veröffentlicht in:	The oncologist (Dayton, Ohio) Ohio), 2021-10, Vol.26 (10), p.835-844
Hauptverfasser:	Huang, Richard S.P., Haberberger, James, McGregor, Kimberly, Mata, Douglas A., Decker, Brennan, Hiemenz, Matthew C., Lechpammer, Mirna, Danziger, Natalie, Schiavone, Kelsie, Creeden, James, Graf, Ryon P., Strowd, Roy, Lesser, Glenn J., Razis, Evangelia D., Bartsch, Rupert, Giannoudis, Athina, Bhogal, Talvinder, Lin, Nancy U., Pusztai, Lajos, Ross, Jeffrey S., Palmieri, Carlo, Ramkissoon, Shakti H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Biomarkers, Tumor - genetics Brain cancer Brain metastases Brain Neoplasms - genetics Breast cancer Breast carcinoma Cancer Cancer Diagnostics and Molecular Pathology Carcinoma Comparative analysis Complications and side effects Comprehensive genomic profiling Demographic aspects Development and progression Diagnosis Fulvestrant Genetic aspects Genomics Humans Immunohistochemistry Medical equipment and supplies industry Medical test kit industry Metastasis Retrospective Studies Risk factors RNA Triple Negative Breast Neoplasms Tumor proteins
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