HAP-Multitag, a PET and Positive MRI Contrast Nanotracer for the Longitudinal Characterization of Vascular Calcifications in Atherosclerosis

Vascular microcalcifications are associated with atherosclerosis plaque instability and, therefore, to increased mortality. Because of this key role, several imaging probes have been developed for their in vivo identification. Among them, [18F]FNa is the gold standard, showing a large uptake in the...

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Veröffentlicht in:	ACS applied materials & interfaces 2021-09, Vol.13 (38), p.45279-45290
Hauptverfasser:	Pellico, Juan, Fernández-Barahona, Irene, Ruiz-Cabello, Jesús, Gutiérrez, Lucía, Muñoz-Hernando, María, Sánchez-Guisado, María J, Aiestaran-Zelaia, Irati, Martínez-Parra, Lydia, Rodríguez, Ignacio, Bentzon, Jacob, Herranz, Fernando
Format:	Artikel
Sprache:	eng
Schlagworte:	Alendronate - chemistry Animals Aorta - pathology Atherosclerosis - complications Atherosclerosis - diagnosis Atherosclerosis - pathology Biological and Medical Applications of Materials and Interfaces Contrast Media - chemistry Durapatite - chemistry Gallium Radioisotopes - chemistry Magnetic Iron Oxide Nanoparticles - chemistry Magnetic Resonance Imaging Mice Multimodal Imaging Plaque, Atherosclerotic - diagnosis Plaque, Atherosclerotic - etiology Plaque, Atherosclerotic - pathology Positron-Emission Tomography Vascular Calcification - diagnostic imaging Vascular Calcification - etiology Vascular Calcification - pathology
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