Safety and efficacy of sFilm-FS, a novel biodegradable fibrin sealant, in Göttingen minipigs

Bleeding during surgical procedures is a common complication. Therefore, hemostatic agents have been developed to control bleeding, and fibrin sealants have several benefits. sFilm-FS is a novel fibrin sealant that comprises a biodegradable co-polymeric film embedded with human fibrinogen and thromb...

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Veröffentlicht in:	Journal of Toxicologic Pathology 2021, Vol.34(4), pp.319-330
Hauptverfasser:	Ramot, Yuval, Steiner, Michal, Lavie, Yossi, Ezov, Nati, Laub, Orgad, Cohen, Eran, Schwartz, Yotam, Nyska, Abraham
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Adverse events animal models Animals Biodegradability biodegradable materials Biodegradation Bleeding Fibrin Fibrinogen Hemostasis Hemostatics Liver local tolerability Organs Original Polymer films Safety Sealants Sealing compounds Spleen Thrombin Thromboembolism
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