Downstaging in Pancreatic Cancer: A Matched Analysis of Patients Resected Following Systemic Treatment of Initially Locally Unresectable Disease

Background Patients with locally unresectable pancreatic cancer (AJCC stage III) have a median survival of 10–14 months. The objective of this study was to evaluate outcome of initially unresectable patients who respond to multimodality therapy and undergo resection. Methods Using a prospectively co...

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Veröffentlicht in:	Annals of surgical oncology 2012-05, Vol.19 (5), p.1663-1669
Hauptverfasser:	Bickenbach, K. A., Gonen, M., Tang, Laura H., O’Reilly, Eileen, Goodman, Karyn, Brennan, M. F., D’Angelica, M. I., DeMatteo, R. P., Fong, Y., Jarnagin, W. R., Allen, P. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - mortality Adenocarcinoma - pathology Adenocarcinoma - secondary Adenocarcinoma - therapy Adult Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - therapeutic use Capecitabine Case-Control Studies Chemoradiotherapy Cisplatin - administration & dosage Cohort Studies Combined Modality Therapy Deoxycytidine - administration & dosage Deoxycytidine - analogs & derivatives Erlotinib Hydrochloride Female Fluorouracil - administration & dosage Fluorouracil - analogs & derivatives Humans Length of Stay Leucovorin - administration & dosage Lymphatic Metastasis Male Medicine Medicine & Public Health Middle Aged Neoplasm Staging Oncology Pancreatic cancer Pancreatic Neoplasms - mortality Pancreatic Neoplasms - pathology Pancreatic Neoplasms - therapy Pancreatic Tumors Pancreaticoduodenectomy Quinazolines - administration & dosage Surgery Surgical Oncology Survival Rate Taxoids - administration & dosage
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