A Pioneer Transcription Factor and Type I Nuclear Hormone Receptors Synergistically Activate the Bovine Herpesvirus 1 Infected Cell Protein 0 (ICP0) Early Promoter

Following bovine herpesvirus 1 (BoHV-1) acute infection of ocular, oral, or nasal cavities, sensory neurons within trigeminal ganglia are an important site for latency. Stress, as mimicked by the synthetic corticosteroid dexamethasone, consistently induces reactivation from latency. Expression of tw...

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Veröffentlicht in:	Journal of virology 2021-09, Vol.95 (20), p.e0076821-e0076821
Hauptverfasser:	Sawant, Laximan, Ostler, Jeffery B, Jones, Clinton
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 Cells Animals Binding Sites Gene Expression Regulation, Viral - genetics Herpesviridae Infections - virology Herpesvirus 1, Bovine - genetics Herpesvirus 1, Bovine - metabolism Host-Microbial Interactions Humans Immediate-Early Proteins - metabolism Kruppel-Like Factor 4 Kruppel-Like Transcription Factors - metabolism Mice Promoter Regions, Genetic - genetics Receptors, Cytoplasmic and Nuclear - genetics Receptors, Cytoplasmic and Nuclear - metabolism Trans-Activators - genetics Trans-Activators - metabolism Transcription Factors - genetics Transcription Factors - metabolism Ubiquitin-Protein Ligases - genetics Ubiquitin-Protein Ligases - metabolism Viral Proteins - metabolism Virus Activation - genetics Virus Latency - genetics Virus Replication Virus-Cell Interactions
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