Evaluation of WNT Signaling Pathway Gene Variants WNT7B rs6519955, SFRP4 rs17171229 and RSPO2 rs611744 in Patients with Dupuytren's Contracture

Dupuytren's contracture (DC) represents a chronic fibroproliferative pathology of the palmar aponeurosis, which leads to flexion contractures of finger joints and hand disability. In recent decades, the WNT signaling pathway has been revealed to play a significant role in the manifestation and...

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Veröffentlicht in:	Genes 2021-08, Vol.12 (9), p.1293
Hauptverfasser:	Samulėnas, Gediminas, Smalinskienė, Alina, Rimdeika, Rytis, Braziulis, Kęstutis, Fomkinas, Mantas, Paškevičius, Rokas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Dupuytren Contracture - genetics Family medical history Female Frizzled protein Gene expression Genomes Genotype & phenotype Genotyping Humans Intercellular Signaling Peptides and Proteins - genetics Male Middle Aged Pathogenesis Peripheral blood Polymorphism, Single Nucleotide Proto-Oncogene Proteins - genetics Signal transduction Single-nucleotide polymorphism Software Statistical analysis Wnt protein Wnt Proteins - genetics
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