Coordinated Fc-effector and neutralization functions in HIV-infected children define a window of opportunity for HIV vaccination

Antibody function has been extensively studied in HIV-infected adults but is relatively understudied in children. Emerging data suggests enhanced development of broadly neutralizing antibodies (bNAbs) in children but Fc effector functions in this group are less well defined. Here, we profiled overal...

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Veröffentlicht in:	AIDS (London) 2021-10, Vol.35 (12), p.1895-1905
Hauptverfasser:	Nduati, Eunice W., Gorman, Mathew J., Sein, Yiakon, Hermanus, Tandile, Yuan, Dansu, Oyaro, Ian, Muema, Daniel M., Ndung’u, Thumbi, Alter, Galit, Moore, Penny L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Neutralizing Antibody-Dependent Cell Cytotoxicity Basic Science Child Child, Preschool Cross-Sectional Studies HIV Antibodies HIV Infections HIV-1 Homeodomain Proteins Humans Infant Nerve Tissue Proteins Vaccination
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