Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer: a retrospective multicentre cohort study

Response to immunotherapy in gastric cancer is associated with microsatellite instability (or mismatch repair deficiency) and Epstein-Barr virus (EBV) positivity. We therefore aimed to develop and validate deep learning-based classifiers to detect microsatellite instability and EBV status from routi...

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Veröffentlicht in:The Lancet. Digital health 2021-10, Vol.3 (10), p.e654-e664
Hauptverfasser: Muti, Hannah Sophie, Heij, Lara Rosaline, Keller, Gisela, Kohlruss, Meike, Langer, Rupert, Dislich, Bastian, Cheong, Jae-Ho, Kim, Young-Woo, Kim, Hyunki, Kook, Myeong-Cherl, Cunningham, David, Allum, William H, Langley, Ruth E, Nankivell, Matthew G, Quirke, Philip, Hayden, Jeremy D, West, Nicholas P, Irvine, Andrew J, Yoshikawa, Takaki, Oshima, Takashi, Huss, Ralf, Grosser, Bianca, Roviello, Franco, d'Ignazio, Alessia, Quaas, Alexander, Alakus, Hakan, Tan, Xiuxiang, Pearson, Alexander T, Luedde, Tom, Ebert, Matthias P, Jäger, Dirk, Trautwein, Christian, Gaisa, Nadine Therese, Grabsch, Heike I, Kather, Jakob Nikolas
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Sprache:eng
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