Are Mobile Persons With Parkinson Disease Necessarily More Active?

BACKGROUND AND PURPOSEWalking activity in persons with Parkinson disease (PD) is important for preventing functional decline. The contribution of walking activity to home and community mobility in PD is poorly understood.METHODSCross-sectional baseline data (N = 69) were analyzed from a randomized c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of neurologic physical therapy 2021-10, Vol.45 (4), p.259-265
Hauptverfasser: Zajac, Jenna A., Cavanaugh, James T., Baker, Teresa, Colón-Semenza, Cristina, DeAngelis, Tamara R., Duncan, Ryan P., Fulford, Daniel, LaValley, Michael, Nordahl, Timothy, Rawson, Kerri S., Saint-Hilaire, Marie, Thomas, Cathi A., Earhart, Gammon M., Ellis, Terry D.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 265
container_issue 4
container_start_page 259
container_title Journal of neurologic physical therapy
container_volume 45
creator Zajac, Jenna A.
Cavanaugh, James T.
Baker, Teresa
Colón-Semenza, Cristina
DeAngelis, Tamara R.
Duncan, Ryan P.
Fulford, Daniel
LaValley, Michael
Nordahl, Timothy
Rawson, Kerri S.
Saint-Hilaire, Marie
Thomas, Cathi A.
Earhart, Gammon M.
Ellis, Terry D.
description BACKGROUND AND PURPOSEWalking activity in persons with Parkinson disease (PD) is important for preventing functional decline. The contribution of walking activity to home and community mobility in PD is poorly understood.METHODSCross-sectional baseline data (N = 69) were analyzed from a randomized controlled PD trial. The Life-Space Assessment (LSA) quantified the extent, frequency, and independence across 5 expanding levels of home and community mobility, producing individual subscores and a total score. Two additional summed scores were used to represent mobility within (Levels 1-3) and beyond (Levels 4-5) neighborhood limits. An accelerometer measured walking activity for 7 days. Regression and correlation analyses evaluated relationships between daily steps and mobility scores. Mann-Whitney U tests secondarily compared differences in mobility scores between the active and sedentary groups.RESULTSWalking activity contributed significantly to the summed Level 1-3 score (β = 0.001, P = 0.004) but not to the summed Level 4-5 (β = 0.001, P = 0.33) or total (β = 0.002, P = 0.07) scores. Walking activity was significantly related to Level 1 (ρ = 0.336, P = 0.005), Level 2 (ρ = 0.307, P = 0.010), and Level 3 (ρ = 0.314, P = 0.009) subscores. Only the summed Level 1-3 score (P = 0.030) was significantly different between the active and sedentary groups.DISCUSSION AND CONCLUSIONSPersons with PD who demonstrated greater mobility beyond the neighborhood were not necessarily more active; walking activity contributed more so to home and neighborhood mobility. Compared with LSA total score, the Level 1-3 summed score may be a more useful participation-level measure for assessing the impact of changes in walking activity.Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1 available at: http://links.lww.com/JNPT/A349).
doi_str_mv 10.1097/NPT.0000000000000362
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8460597</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2583114341</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4573-9611108471d957056210506740f9c98ed1cbdff5af3b4b0195408efdaaa6dbc03</originalsourceid><addsrcrecordid>eNpdkctuFDEQRS0EIiHwByxarNh0KLffG9CQhIeUhFkEsbTc7mrGxNMe7J5E-Xs8JAoktbGtOve6VJeQ1xQOKRj17nx5cQj_F5PdE7JPhVAtCM2f3t-V3CMvSvkF0CmuzHOyxzgYKqTZJx8XGZuz1IeIzRJzSVNpfoR51SxdvgxTfTfHoaAr2Jyjx1JcDvGmKqps4edwhR9ekmejiwVf3Z0H5Punk4ujL-3pt89fjxanredCsdZISiloruhghAIhOwoCpOIwGm80DtT3wzgKN7Ke90CN4KBxHJxzcug9sAPy_tZ3s-3XOHic5uyi3eSwdvnGJhfsw84UVvZnurKaSxBGVYM3dwY5_d5imW3GTcpzsZ3QjFLOOK3Q20fQOhSPMboJ03aHMg1car1D-S3qcyol43g_CwW7y8jWjOzjjP7JrlOc68ov4_Yas12hi_PKAq0_gJZtB13dV632r5D9AY-AkQw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2538046881</pqid></control><display><type>article</type><title>Are Mobile Persons With Parkinson Disease Necessarily More Active?</title><source>EZB-FREE-00999 freely available EZB journals</source><creator>Zajac, Jenna A. ; Cavanaugh, James T. ; Baker, Teresa ; Colón-Semenza, Cristina ; DeAngelis, Tamara R. ; Duncan, Ryan P. ; Fulford, Daniel ; LaValley, Michael ; Nordahl, Timothy ; Rawson, Kerri S. ; Saint-Hilaire, Marie ; Thomas, Cathi A. ; Earhart, Gammon M. ; Ellis, Terry D.</creator><creatorcontrib>Zajac, Jenna A. ; Cavanaugh, James T. ; Baker, Teresa ; Colón-Semenza, Cristina ; DeAngelis, Tamara R. ; Duncan, Ryan P. ; Fulford, Daniel ; LaValley, Michael ; Nordahl, Timothy ; Rawson, Kerri S. ; Saint-Hilaire, Marie ; Thomas, Cathi A. ; Earhart, Gammon M. ; Ellis, Terry D.</creatorcontrib><description>BACKGROUND AND PURPOSEWalking activity in persons with Parkinson disease (PD) is important for preventing functional decline. The contribution of walking activity to home and community mobility in PD is poorly understood.METHODSCross-sectional baseline data (N = 69) were analyzed from a randomized controlled PD trial. The Life-Space Assessment (LSA) quantified the extent, frequency, and independence across 5 expanding levels of home and community mobility, producing individual subscores and a total score. Two additional summed scores were used to represent mobility within (Levels 1-3) and beyond (Levels 4-5) neighborhood limits. An accelerometer measured walking activity for 7 days. Regression and correlation analyses evaluated relationships between daily steps and mobility scores. Mann-Whitney U tests secondarily compared differences in mobility scores between the active and sedentary groups.RESULTSWalking activity contributed significantly to the summed Level 1-3 score (β = 0.001, P = 0.004) but not to the summed Level 4-5 (β = 0.001, P = 0.33) or total (β = 0.002, P = 0.07) scores. Walking activity was significantly related to Level 1 (ρ = 0.336, P = 0.005), Level 2 (ρ = 0.307, P = 0.010), and Level 3 (ρ = 0.314, P = 0.009) subscores. Only the summed Level 1-3 score (P = 0.030) was significantly different between the active and sedentary groups.DISCUSSION AND CONCLUSIONSPersons with PD who demonstrated greater mobility beyond the neighborhood were not necessarily more active; walking activity contributed more so to home and neighborhood mobility. Compared with LSA total score, the Level 1-3 summed score may be a more useful participation-level measure for assessing the impact of changes in walking activity.Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1 available at: http://links.lww.com/JNPT/A349).</description><identifier>ISSN: 1557-0576</identifier><identifier>EISSN: 1557-0584</identifier><identifier>DOI: 10.1097/NPT.0000000000000362</identifier><identifier>PMID: 34091569</identifier><language>eng</language><publisher>LaCrosse: Wolters Kluwer Health, Inc</publisher><subject>Activities of daily living ; Clinical trials ; Mobility ; Parkinson's disease ; Studies ; Walking</subject><ispartof>Journal of neurologic physical therapy, 2021-10, Vol.45 (4), p.259-265</ispartof><rights>Wolters Kluwer Health, Inc.</rights><rights>Copyright Neurology Section - American Physical Therapy Association Oct 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4573-9611108471d957056210506740f9c98ed1cbdff5af3b4b0195408efdaaa6dbc03</citedby><cites>FETCH-LOGICAL-c4573-9611108471d957056210506740f9c98ed1cbdff5af3b4b0195408efdaaa6dbc03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids></links><search><creatorcontrib>Zajac, Jenna A.</creatorcontrib><creatorcontrib>Cavanaugh, James T.</creatorcontrib><creatorcontrib>Baker, Teresa</creatorcontrib><creatorcontrib>Colón-Semenza, Cristina</creatorcontrib><creatorcontrib>DeAngelis, Tamara R.</creatorcontrib><creatorcontrib>Duncan, Ryan P.</creatorcontrib><creatorcontrib>Fulford, Daniel</creatorcontrib><creatorcontrib>LaValley, Michael</creatorcontrib><creatorcontrib>Nordahl, Timothy</creatorcontrib><creatorcontrib>Rawson, Kerri S.</creatorcontrib><creatorcontrib>Saint-Hilaire, Marie</creatorcontrib><creatorcontrib>Thomas, Cathi A.</creatorcontrib><creatorcontrib>Earhart, Gammon M.</creatorcontrib><creatorcontrib>Ellis, Terry D.</creatorcontrib><title>Are Mobile Persons With Parkinson Disease Necessarily More Active?</title><title>Journal of neurologic physical therapy</title><description>BACKGROUND AND PURPOSEWalking activity in persons with Parkinson disease (PD) is important for preventing functional decline. The contribution of walking activity to home and community mobility in PD is poorly understood.METHODSCross-sectional baseline data (N = 69) were analyzed from a randomized controlled PD trial. The Life-Space Assessment (LSA) quantified the extent, frequency, and independence across 5 expanding levels of home and community mobility, producing individual subscores and a total score. Two additional summed scores were used to represent mobility within (Levels 1-3) and beyond (Levels 4-5) neighborhood limits. An accelerometer measured walking activity for 7 days. Regression and correlation analyses evaluated relationships between daily steps and mobility scores. Mann-Whitney U tests secondarily compared differences in mobility scores between the active and sedentary groups.RESULTSWalking activity contributed significantly to the summed Level 1-3 score (β = 0.001, P = 0.004) but not to the summed Level 4-5 (β = 0.001, P = 0.33) or total (β = 0.002, P = 0.07) scores. Walking activity was significantly related to Level 1 (ρ = 0.336, P = 0.005), Level 2 (ρ = 0.307, P = 0.010), and Level 3 (ρ = 0.314, P = 0.009) subscores. Only the summed Level 1-3 score (P = 0.030) was significantly different between the active and sedentary groups.DISCUSSION AND CONCLUSIONSPersons with PD who demonstrated greater mobility beyond the neighborhood were not necessarily more active; walking activity contributed more so to home and neighborhood mobility. Compared with LSA total score, the Level 1-3 summed score may be a more useful participation-level measure for assessing the impact of changes in walking activity.Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1 available at: http://links.lww.com/JNPT/A349).</description><subject>Activities of daily living</subject><subject>Clinical trials</subject><subject>Mobility</subject><subject>Parkinson's disease</subject><subject>Studies</subject><subject>Walking</subject><issn>1557-0576</issn><issn>1557-0584</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNpdkctuFDEQRS0EIiHwByxarNh0KLffG9CQhIeUhFkEsbTc7mrGxNMe7J5E-Xs8JAoktbGtOve6VJeQ1xQOKRj17nx5cQj_F5PdE7JPhVAtCM2f3t-V3CMvSvkF0CmuzHOyxzgYKqTZJx8XGZuz1IeIzRJzSVNpfoR51SxdvgxTfTfHoaAr2Jyjx1JcDvGmKqps4edwhR9ekmejiwVf3Z0H5Punk4ujL-3pt89fjxanredCsdZISiloruhghAIhOwoCpOIwGm80DtT3wzgKN7Ke90CN4KBxHJxzcug9sAPy_tZ3s-3XOHic5uyi3eSwdvnGJhfsw84UVvZnurKaSxBGVYM3dwY5_d5imW3GTcpzsZ3QjFLOOK3Q20fQOhSPMboJ03aHMg1car1D-S3qcyol43g_CwW7y8jWjOzjjP7JrlOc68ov4_Yas12hi_PKAq0_gJZtB13dV632r5D9AY-AkQw</recordid><startdate>20211001</startdate><enddate>20211001</enddate><creator>Zajac, Jenna A.</creator><creator>Cavanaugh, James T.</creator><creator>Baker, Teresa</creator><creator>Colón-Semenza, Cristina</creator><creator>DeAngelis, Tamara R.</creator><creator>Duncan, Ryan P.</creator><creator>Fulford, Daniel</creator><creator>LaValley, Michael</creator><creator>Nordahl, Timothy</creator><creator>Rawson, Kerri S.</creator><creator>Saint-Hilaire, Marie</creator><creator>Thomas, Cathi A.</creator><creator>Earhart, Gammon M.</creator><creator>Ellis, Terry D.</creator><general>Wolters Kluwer Health, Inc</general><general>Neurology Section - American Physical Therapy Association</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>4T-</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>5PM</scope></search><sort><creationdate>20211001</creationdate><title>Are Mobile Persons With Parkinson Disease Necessarily More Active?</title><author>Zajac, Jenna A. ; Cavanaugh, James T. ; Baker, Teresa ; Colón-Semenza, Cristina ; DeAngelis, Tamara R. ; Duncan, Ryan P. ; Fulford, Daniel ; LaValley, Michael ; Nordahl, Timothy ; Rawson, Kerri S. ; Saint-Hilaire, Marie ; Thomas, Cathi A. ; Earhart, Gammon M. ; Ellis, Terry D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4573-9611108471d957056210506740f9c98ed1cbdff5af3b4b0195408efdaaa6dbc03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Activities of daily living</topic><topic>Clinical trials</topic><topic>Mobility</topic><topic>Parkinson's disease</topic><topic>Studies</topic><topic>Walking</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zajac, Jenna A.</creatorcontrib><creatorcontrib>Cavanaugh, James T.</creatorcontrib><creatorcontrib>Baker, Teresa</creatorcontrib><creatorcontrib>Colón-Semenza, Cristina</creatorcontrib><creatorcontrib>DeAngelis, Tamara R.</creatorcontrib><creatorcontrib>Duncan, Ryan P.</creatorcontrib><creatorcontrib>Fulford, Daniel</creatorcontrib><creatorcontrib>LaValley, Michael</creatorcontrib><creatorcontrib>Nordahl, Timothy</creatorcontrib><creatorcontrib>Rawson, Kerri S.</creatorcontrib><creatorcontrib>Saint-Hilaire, Marie</creatorcontrib><creatorcontrib>Thomas, Cathi A.</creatorcontrib><creatorcontrib>Earhart, Gammon M.</creatorcontrib><creatorcontrib>Ellis, Terry D.</creatorcontrib><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Docstoc</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of neurologic physical therapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zajac, Jenna A.</au><au>Cavanaugh, James T.</au><au>Baker, Teresa</au><au>Colón-Semenza, Cristina</au><au>DeAngelis, Tamara R.</au><au>Duncan, Ryan P.</au><au>Fulford, Daniel</au><au>LaValley, Michael</au><au>Nordahl, Timothy</au><au>Rawson, Kerri S.</au><au>Saint-Hilaire, Marie</au><au>Thomas, Cathi A.</au><au>Earhart, Gammon M.</au><au>Ellis, Terry D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Are Mobile Persons With Parkinson Disease Necessarily More Active?</atitle><jtitle>Journal of neurologic physical therapy</jtitle><date>2021-10-01</date><risdate>2021</risdate><volume>45</volume><issue>4</issue><spage>259</spage><epage>265</epage><pages>259-265</pages><issn>1557-0576</issn><eissn>1557-0584</eissn><abstract>BACKGROUND AND PURPOSEWalking activity in persons with Parkinson disease (PD) is important for preventing functional decline. The contribution of walking activity to home and community mobility in PD is poorly understood.METHODSCross-sectional baseline data (N = 69) were analyzed from a randomized controlled PD trial. The Life-Space Assessment (LSA) quantified the extent, frequency, and independence across 5 expanding levels of home and community mobility, producing individual subscores and a total score. Two additional summed scores were used to represent mobility within (Levels 1-3) and beyond (Levels 4-5) neighborhood limits. An accelerometer measured walking activity for 7 days. Regression and correlation analyses evaluated relationships between daily steps and mobility scores. Mann-Whitney U tests secondarily compared differences in mobility scores between the active and sedentary groups.RESULTSWalking activity contributed significantly to the summed Level 1-3 score (β = 0.001, P = 0.004) but not to the summed Level 4-5 (β = 0.001, P = 0.33) or total (β = 0.002, P = 0.07) scores. Walking activity was significantly related to Level 1 (ρ = 0.336, P = 0.005), Level 2 (ρ = 0.307, P = 0.010), and Level 3 (ρ = 0.314, P = 0.009) subscores. Only the summed Level 1-3 score (P = 0.030) was significantly different between the active and sedentary groups.DISCUSSION AND CONCLUSIONSPersons with PD who demonstrated greater mobility beyond the neighborhood were not necessarily more active; walking activity contributed more so to home and neighborhood mobility. Compared with LSA total score, the Level 1-3 summed score may be a more useful participation-level measure for assessing the impact of changes in walking activity.Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1 available at: http://links.lww.com/JNPT/A349).</abstract><cop>LaCrosse</cop><pub>Wolters Kluwer Health, Inc</pub><pmid>34091569</pmid><doi>10.1097/NPT.0000000000000362</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1557-0576
ispartof Journal of neurologic physical therapy, 2021-10, Vol.45 (4), p.259-265
issn 1557-0576
1557-0584
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8460597
source EZB-FREE-00999 freely available EZB journals
subjects Activities of daily living
Clinical trials
Mobility
Parkinson's disease
Studies
Walking
title Are Mobile Persons With Parkinson Disease Necessarily More Active?
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T20%3A37%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Are%20Mobile%20Persons%20With%20Parkinson%20Disease%20Necessarily%20More%20Active?&rft.jtitle=Journal%20of%20neurologic%20physical%20therapy&rft.au=Zajac,%20Jenna%20A.&rft.date=2021-10-01&rft.volume=45&rft.issue=4&rft.spage=259&rft.epage=265&rft.pages=259-265&rft.issn=1557-0576&rft.eissn=1557-0584&rft_id=info:doi/10.1097/NPT.0000000000000362&rft_dat=%3Cproquest_pubme%3E2583114341%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2538046881&rft_id=info:pmid/34091569&rfr_iscdi=true