A Probabilistic Classification Tool for Genetic Subtypes of Diffuse Large B Cell Lymphoma with Therapeutic Implications

The development of precision medicine approaches for diffuse large B cell lymphoma (DLBCL) is confounded by its pronounced genetic, phenotypic, and clinical heterogeneity. Recent multiplatform genomic studies revealed the existence of genetic subtypes of DLBCL using clustering methodologies. Here, w...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer cell 2020-04, Vol.37 (4), p.551-568.e14
Hauptverfasser:	Wright, George W., Huang, Da Wei, Phelan, James D., Coulibaly, Zana A., Roulland, Sandrine, Young, Ryan M., Wang, James Q., Schmitz, Roland, Morin, Ryan D., Tang, Jeffrey, Jiang, Aixiang, Bagaev, Aleksander, Plotnikova, Olga, Kotlov, Nikita, Johnson, Calvin A., Wilson, Wyndham H., Scott, David W., Staudt, Louis M.
Format:	Artikel
Sprache:	eng
Schlagworte:	A53 Animals Apoptosis Biomarkers, Tumor - genetics BN2 Cell Proliferation DLBCL EZB Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Genetic Heterogeneity genomic classification Humans LymphGen lymphoma Lymphoma, Large B-Cell, Diffuse - classification Lymphoma, Large B-Cell, Diffuse - drug therapy Lymphoma, Large B-Cell, Diffuse - genetics Lymphoma, Large B-Cell, Diffuse - pathology MCD Mice Mice, Inbred NOD Mice, SCID Molecular Targeted Therapy naive Bayes Precision Medicine ST2 Tumor Cells, Cultured Tumor Microenvironment Xenograft Model Antitumor Assays
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!