Semi-Synthesis of New 1,2,3-Triazole Derivatives of 9-Bromonoscapine and their Anticancer Activities

Novel 1,2,3-triazole-tethered 9-bromonoscapine derivatives were synthesized by the propargylation of N-nornoscapine followed by Huisgen’s 1,3-dipolar cycloaddition of the terminal alkynes with different azides. Cytotoxicity of the products was studied by MTT assay against the MCF-7 breast cancer cel...

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Veröffentlicht in:	Iranian journal of pharmaceutical research : IJPR 2021-01, Vol.20 (2), p.546-560
Hauptverfasser:	Hasanpour, Zahra, Salehi, Peyman, Bararjanian, Morteza, Esmaeili, Mohammad-Ali, Alilou, Mostafa, Mohebbi, Maryam
Format:	Artikel
Sprache:	eng
Schlagworte:	Original
Online-Zugang:	Volltext
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