Photoredox-mediated hydroalkylation and hydroarylation of functionalized olefins for DNA-encoded library synthesis

DNA-encoded library (DEL) technology features a time- and cost-effective interrogation format for the discovery of therapeutic candidates in the pharmaceutical industry. To develop DEL platforms, the implementation of water-compatible transformations that facilitate the incorporation of multifunctio...

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Veröffentlicht in:	Chemical science (Cambridge) 2021-09, Vol.12 (36), p.1236-1245
Hauptverfasser:	Badir, Shorouk O, Lipp, Alexander, Krumb, Matthias, Cabrera-Afonso, María Jesús, Kammer, Lisa Marie, Wu, Victoria E, Huang, Minxue, Csakai, Adam, Marcaurelle, Lisa A, Molander, Gary A
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkenes Chemistry Chemistry, Multidisciplinary Coordination compounds Electron transfer Functional groups Industrial development Interrogation Libraries Light irradiation Photoredox catalysis Physical Sciences Science & Technology Single electrons
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