Structural basis for the hyperthermostability of an archaeal enzyme induced by succinimide formation

Stability of proteins from hyperthermophiles (organisms existing under boiling water conditions) enabled by a reduction of conformational flexibility is realized through various mechanisms. A succinimide (SNN) arising from the post-translational cyclization of the side chains of aspartyl/asparaginyl...

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Veröffentlicht in:	Biophysical journal 2021-09, Vol.120 (17), p.3732-3746
Hauptverfasser:	Dongre, Aparna Vilas, Das, Sudip, Bellur, Asutosh, Kumar, Sanjeev, Chandrashekarmath, Anusha, Karmakar, Tarak, Balaram, Padmanabhan, Balasubramanian, Sundaram, Balaram, Hemalatha
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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