Medical Records-Based Genetic Studies of the Complement System

Genetic variants in complement genes have been associated with a wide range of human disease states, but well-powered genetic association studies of complement activation have not been performed in large multiethnic cohorts. We performed medical records-based genome-wide and phenome-wide association...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2021-08, Vol.32 (8), p.2031-2047
Hauptverfasser:	Khan, Atlas, Shang, Ning, Petukhova, Lynn, Zhang, Jun, Shen, Yufeng, Hebbring, Scott J, Moncrieffe, Halima, Kottyan, Leah C, Namjou-Khales, Bahram, Knevel, Rachel, Raychaudhuri, Soumya, Karlson, Elizabeth W, Harley, John B, Stanaway, Ian B, Crosslin, David, Denny, Joshua C, Elkind, Mitchell S V, Gharavi, Ali G, Hripcsak, George, Weng, Chunhua, Kiryluk, Krzysztof
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alleles Clinical Research Complement Activation - genetics Complement C3 - genetics Complement C3 - metabolism Complement C4 - genetics Complement C4 - metabolism Databases, Genetic Epidemiologic Studies Female Gene Dosage Genetic Loci Genetic Variation Genome-Wide Association Study Humans Male Medical Record Linkage Medical Records Middle Aged Young Adult
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