Abnormally elevated ubiquilin-1 expression in breast cancer regulates metastasis and stemness via AKT signaling

Ubiquilin-1 (UBQLN1) is an essential factor for the maintenance of proteostasis in cells. It is important for the regulation of different protein degradation mechanisms, including the ubiquitin-proteasome system, autophagy and endoplasmic reticulum-associated protein degradation pathways. However, t...

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