OFF-State-Specific Inhibition of the Proprotein Convertase Furin

The pro-protein convertase furin is a highly specific serine protease involved in the proteolytic maturation of many proteins in the secretory pathway. It also activates surface proteins of many viruses including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Furin inhibitors effe...

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Veröffentlicht in:	ACS chemical biology 2021-09, Vol.16 (9), p.1692-1700
Hauptverfasser:	Dahms, Sven O, Haider, Tanja, Klebe, Gerhard, Steinmetzer, Torsten, Brandstetter, Hans
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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