Can we reduce oxidative stress with liver transplantation?

Can we reduce oxidative stress with liver transplantation?

The aim of this study was to determine the levels of lipid peroxidation (MDA) and antioxidants such as reduced glutathione (GSH), catalase (CAT) and superoxide dismutase (SOD) in the blood serum of patients with cirrhosis and liver transplantation. In this study, serum malondialdehyde acid (MDA) lev...

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Veröffentlicht in:Journal of medical biochemistry 2021-09, Vol.40 (4), p.351-357
Hauptverfasser: Aydin, Mesut, Dirik, Yaren, Demir, Canan, Tolunay, Harun Egemen, Demir, Halit
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container_issue 4
container_start_page 351
container_title Journal of medical biochemistry
container_volume 40
creator Aydin, Mesut
Dirik, Yaren
Demir, Canan
Tolunay, Harun Egemen
Demir, Halit
description The aim of this study was to determine the levels of lipid peroxidation (MDA) and antioxidants such as reduced glutathione (GSH), catalase (CAT) and superoxide dismutase (SOD) in the blood serum of patients with cirrhosis and liver transplantation. In this study, serum malondialdehyde acid (MDA) levels, superoxide dismutase (SOD), reduced glutathione (GSH), and catalase (CAT) activities were measured spectrophotometrically and compared to the results of the healthy control group. SOD, CAT and GSH activities were significantly decreased in the patient groups compared to the healthy control group (p
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In this study, serum malondialdehyde acid (MDA) levels, superoxide dismutase (SOD), reduced glutathione (GSH), and catalase (CAT) activities were measured spectrophotometrically and compared to the results of the healthy control group. SOD, CAT and GSH activities were significantly decreased in the patient groups compared to the healthy control group (p&lt;0.05). MDA levels were significantly higher in the patient group compared to the healthy control group (p &lt;0.05). In conclusion, this study demonstrated that oxidative stress may play an important role in the development of liver cirrhosis and in liver transplantation. 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title Can we reduce oxidative stress with liver transplantation?
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