Effect of Early High-Dose Vitamin D3 Repletion on Cognitive Outcomes in Critically Ill Adults

Long-term cognitive impairment frequently occurs after critical illness; no treatments are known to improve long-term cognition. Does a single high-dose (540,000 International Units) enteral treatment of vitamin D3 given shortly after hospital admission in critically ill patients who are vitamin D d...

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Veröffentlicht in:	Chest 2021-09, Vol.160 (3), p.909-918
Hauptverfasser:	Han, Jin H., Ginde, Adit A., Brown, Samuel M., Baughman, Adrienne, Collar, Erin M., Ely, E. Wesley, Gong, Michelle N., Hope, Aluko A., Hou, Peter C., Hough, Catherine L., Iwashyna, Theodore J., Jackson, James C., Khan, Akram, Orun, Onur M., Patel, Mayur B., Raman, Rameela, Rice, Todd W., Ringwood, Nancy, Semler, Matthew W., Shapiro, Nathan I., Talmor, Daniel S., Self, Wesley H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cholecalciferol - administration & dosage Cognition - drug effects Cognitive Dysfunction - diagnosis Cognitive Dysfunction - drug therapy Cognitive Dysfunction - etiology Critical Care: Original Research Critical Illness - psychology Critical Illness - rehabilitation executive function Executive Function - drug effects Female global cognition Humans ICU Long Term Adverse Effects - diagnosis Long Term Adverse Effects - drug therapy Long Term Adverse Effects - etiology Long Term Adverse Effects - psychology Male Middle Aged Neuropsychological Tests Pulse Therapy, Drug - methods Treatment Outcome vitamin D Vitamin D Deficiency - drug therapy Vitamin D Deficiency - psychology Vitamins - administration & dosage
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