Plasma and Lung Tissue Pharmacokinetics of Ceftaroline Fosamil in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass: an In Vivo Microdialysis Study

Ceftaroline fosamil, a fifth-generation cephalosporin antibiotic with activity against methicillin-resistant Staphylococcus aureus (MRSA), is currently approved for the treatment of pneumonia and complicated skin and soft tissue infections. However, pharmacokinetics data on free lung tissue concentr...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2021-09, Vol.65 (10), p.e0067921
Hauptverfasser:	Edlinger-Stanger, M, Al Jalali, V, Andreas, M, Jäger, W, Böhmdorfer, M, Zeitlinger, M, Hutschala, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - therapeutic use Cardiac Surgical Procedures Cardiopulmonary Bypass Ceftaroline Cephalosporins Humans Lung - surgery Methicillin-Resistant Staphylococcus aureus Microdialysis Pharmaceutical Preparations Pharmacology
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