Non‐structural protein 1‐specific antibodies directed against Zika virus in humans mediate antibody‐dependent cellular cytotoxicity

There is growing interest in understanding antibody (Ab) function beyond neutralization. The non‐structural protein 1 (NS1) of Zika virus (ZIKV) is an attractive candidate for an effective vaccine as Abs against NS1, unlike the envelope or premembrane, do not carry the risk of mediating antibody‐dep...

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Veröffentlicht in:Immunology 2021-10, Vol.164 (2), p.386-397
Hauptverfasser: Sanchez Vargas, Luis A., Adam, Awadalkareem, Masterson, Mary, Smith, Madison, Lyski, Zoe L., Dowd, Kimberly A., Pierson, Theodore C., Messer, William B., Currier, Jeffrey R., Mathew, Anuja
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