Early-Onset Cerebral Amyloid Angiopathy and Alzheimer Disease Related to an APP Locus Triplication

To report a triplication of the amyloid-β precursor protein ( ) locus along with relative messenger RNA (mRNA) expression in a family with autosomal dominant early-onset cerebral amyloid angiopathy (CAA) and Alzheimer disease (AD). Four copies of the gene were identified by quantitative multiplex PC...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Neurology. Genetics 2021-10, Vol.7 (5), p.e609-e609
Hauptverfasser:	Grangeon, Lou, Cassinari, Kévin, Rousseau, Stéphane, Croisile, Bernard, Formaglio, Maïté, Moreaud, Olivier, Boutonnat, Jean, Le Meur, Nathalie, Miné, Manuele, Coste, Thibault, Pipiras, Eva, Tournier-Lasserve, Elisabeth, Rovelet-Lecrux, Anne, Campion, Dominique, Wallon, David, Nicolas, Gael
Format:	Artikel
Sprache:	eng
Schlagworte:	Human health and pathology Life Sciences Neurons and Cognition
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!