Hsa_circ_0134111 promotes osteoarthritis progression by regulating miR-224-5p/CCL1 interaction

Mechanical, metabolic, inflammatory, and immune factors contribute to the development of osteoarthritis (OA), a joint disease characterized by cartilage destruction. The circular RNA (circRNA) hsa_circ_0134111 is upregulated in the cartilage of OA patients; however, its potential role in OA pathogen...

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Veröffentlicht in:	Aging (Albany, NY.) NY.), 2021-08, Vol.13 (16), p.20383-20394
Hauptverfasser:	Liu, Yongbao, Zhang, Yanxiu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Chemokine CCL1 - genetics Chemokine CCL1 - metabolism Chondrocytes - metabolism Disease Progression Humans Interleukin-1beta - genetics Interleukin-1beta - metabolism MicroRNAs - genetics MicroRNAs - metabolism Osteoarthritis - genetics Osteoarthritis - metabolism Osteoarthritis - pathology Osteoarthritis - physiopathology Rats Rats, Wistar Research Paper RNA, Circular - genetics RNA, Circular - metabolism
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