Pancreatic Lineage Specifier PDX1 Increases Adhesion and Decreases Motility of Cancer Cells

Intercellular interactions involving adhesion factors are key operators in cancer progression. In particular, these factors are responsible for facilitating cell migration and metastasis. Strengthening of adhesion between tumor cells and surrounding cells or extracellular matrix (ECM), may provide a...

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Veröffentlicht in:	Cancers 2021-08, Vol.13 (17), p.4390
Hauptverfasser:	Kondratyeva, Liya, Chernov, Igor, Kopantzev, Eugene, Didych, Dmitry, Kuzmich, Alexey, Alekseenko, Irina, Kostrov, Sergey, Sverdlov, Eugene
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Cell adhesion Cell adhesion & migration Cell growth Cell migration Collagen (type I) Ectopic expression Extracellular matrix Fibronectin Gene expression Kinases Laboratories Lysine Membranes Mesenchyme Metastases Metastasis Motility Mutation Pancreatic cancer Penicillin Solid tumors Stromal cells Transcription factors Tumor cell lines Tumor cells
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