miR-497-5p induces apoptosis in K562 cells by downregulating ROCK1

OBJECTIVETo validate the role of miR-497-5p in apoptosis in K562 cells by targeting Rho-associated kinase isoform 1 (ROCK1). METHODSFrom January, 2017 to February, 2019, 57 patients with chronic myeloid leukemia (CML) treated in our hospital were included in patient group, and 50 healthy individuals...

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Veröffentlicht in:	American journal of translational research 2021-01, Vol.13 (8), p.9278-9284
Hauptverfasser:	Chen, Nafei, Meng, Zhen, Song, Jiaojie, Kong, Lingfang, Zhang, Yehua, Guo, Suli, Zhang, Xiaokun, Lu, Xin, Jiang, Licai, Chen, Ran, Jiao, Zongjiu, Zhao, Liyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Original
Online-Zugang:	Volltext
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