Degree of Creeping Fat Assessed by Computed Tomography Enterography is Associated with Intestinal Fibrotic Stricture in Patients with Crohn's Disease: A Potentially Novel Mesenteric Creeping Fat Index
Emerging evidence points to a link between creeping fat and the pathogenesis of Crohn's disease [CD]. Non-invasive assessment of the severity of creeping fat on cross-sectional imaging modality has seldom been investigated. This study aimed to develop and characterize a novel mesenteric creepin...
Gespeichert in:
| Veröffentlicht in: | Journal of Crohn's and colitis 2021-07, Vol.15 (7), p.1161-1173 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1173 |
|---|---|
| container_issue | 7 |
| container_start_page | 1161 |
| container_title | Journal of Crohn's and colitis |
| container_volume | 15 |
| creator | Li, Xue-Hua Feng, Shi-Ting Cao, Qing-Hua Coffey, J Calvin Baker, Mark E Huang, Li Fang, Zhuang-Nian Qiu, Yun Lu, Bao-Lan Chen, Zhi-Hui Li, Yi Bettenworth, Dominik Iacucci, Marietta Sun, Can-Hui Ghosh, Subrata Rieder, Florian Chen, Min-Hu Li, Zi-Ping Mao, Ren |
| description | Emerging evidence points to a link between creeping fat and the pathogenesis of Crohn's disease [CD]. Non-invasive assessment of the severity of creeping fat on cross-sectional imaging modality has seldom been investigated. This study aimed to develop and characterize a novel mesenteric creeping fat index [MCFI] based on computed tomography [CT] in CD patients.
MCFI was developed based on vascular findings on CT in a retrospective cohort [n = 91] and validated in a prospective cohort [n = 30]. The severity of creeping fat was graded based on the extent to which mesenteric fat extended around the intestinal circumference using the vessels in the fat as a marker. The accuracy of MCFI was assessed by comparing it with the degree of creeping fat observed in surgical specimens. The relationship between MCFI and fibrostenosis was characterized by determining if these correlated. The accuracy of MCFI was compared with other radiographic indices [i.e. visceral to subcutaneous fat area ratio and fibrofatty proliferation score].
In the retrospective cohort, MCFI had moderate accuracy in differentiating moderate-severe from mild fibrostenosis (area under the receiver operating characteristic [ROC] curve [AUC] = 0.799; p = 0.000). ROC analysis in the retrospective cohort identified a threshold MCFI of > 3 which accurately differentiated fibrostenosis severity in the prospective cohort [AUC = 0.756; p = 0.018]. An excellent correlation was shown between MCFI and the extent of fat wrapping in specimens in the prospective cohort [r = 0.840, p = 0.000]. Neither visceral to subcutaneous fat area ratio nor fibrofatty proliferation score correlated well with the degree of intestinal fibrosis.
MCFI can accurately characterize the extent of mesenteric fat wrapping in surgical specimens. It may become another non-invasive measure of CD fibrostenosis. |
| doi_str_mv | 10.1093/ecco-jcc/jjab005 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8427713</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2476567487</sourcerecordid><originalsourceid>FETCH-LOGICAL-c396t-647395b374f656c5f5f35f6dbfe31ed61cbd634cdd3f358df10fc29107300a943</originalsourceid><addsrcrecordid>eNpVUsFu1DAUtBCIloU7J-QbXELttRPHHJBWaRdWKlCJcrYc52XXqyQOtlPYP-SzcNhtRSVLz9bMmzfyG4ReU_KeEskuwBiX7Y252O91TUj-BJ3TUhQZ50I-_XdnmZS8OEMvQtgngsxF-RydMcYpLSU7R38uYesBsGtxlepohy1e64hXIUA6Da4PuHL9OMV0v3W923o97g74aojg7x82zHxnrJ5Zv2zc4U3CQ7SD7vDa1t5Fa_D36K2JkwdsB3yjo4UhhiO98m43vA340gbQAT7gFb5xMeFWd90Bf3V30OEvEGAem6Qeed0MDfx-iZ61ugvw6lQX6Mf66rb6nF1_-7SpVteZYbKIWcEFk3nNBG-LvDB5m7csb4umboFRaApq6qZg3DQNS0DZtJS0ZikpEYwQLTlboI9H3XGqe2hMcuR1p0Zve-0PymmrHiOD3amtu1MlXwpBWRJ4dxLw7ueUPkn1NhjoOj2Am4JacpGcCZ52t0DkSDXeheChfRhDiZoDoOYAqBQAdQpAannzv72HhvuNs7-djLTu</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2476567487</pqid></control><display><type>article</type><title>Degree of Creeping Fat Assessed by Computed Tomography Enterography is Associated with Intestinal Fibrotic Stricture in Patients with Crohn's Disease: A Potentially Novel Mesenteric Creeping Fat Index</title><source>MEDLINE</source><source>Oxford University Press Journals All Titles (1996-Current)</source><source>Alma/SFX Local Collection</source><creator>Li, Xue-Hua ; Feng, Shi-Ting ; Cao, Qing-Hua ; Coffey, J Calvin ; Baker, Mark E ; Huang, Li ; Fang, Zhuang-Nian ; Qiu, Yun ; Lu, Bao-Lan ; Chen, Zhi-Hui ; Li, Yi ; Bettenworth, Dominik ; Iacucci, Marietta ; Sun, Can-Hui ; Ghosh, Subrata ; Rieder, Florian ; Chen, Min-Hu ; Li, Zi-Ping ; Mao, Ren</creator><creatorcontrib>Li, Xue-Hua ; Feng, Shi-Ting ; Cao, Qing-Hua ; Coffey, J Calvin ; Baker, Mark E ; Huang, Li ; Fang, Zhuang-Nian ; Qiu, Yun ; Lu, Bao-Lan ; Chen, Zhi-Hui ; Li, Yi ; Bettenworth, Dominik ; Iacucci, Marietta ; Sun, Can-Hui ; Ghosh, Subrata ; Rieder, Florian ; Chen, Min-Hu ; Li, Zi-Ping ; Mao, Ren</creatorcontrib><description>Emerging evidence points to a link between creeping fat and the pathogenesis of Crohn's disease [CD]. Non-invasive assessment of the severity of creeping fat on cross-sectional imaging modality has seldom been investigated. This study aimed to develop and characterize a novel mesenteric creeping fat index [MCFI] based on computed tomography [CT] in CD patients.
MCFI was developed based on vascular findings on CT in a retrospective cohort [n = 91] and validated in a prospective cohort [n = 30]. The severity of creeping fat was graded based on the extent to which mesenteric fat extended around the intestinal circumference using the vessels in the fat as a marker. The accuracy of MCFI was assessed by comparing it with the degree of creeping fat observed in surgical specimens. The relationship between MCFI and fibrostenosis was characterized by determining if these correlated. The accuracy of MCFI was compared with other radiographic indices [i.e. visceral to subcutaneous fat area ratio and fibrofatty proliferation score].
In the retrospective cohort, MCFI had moderate accuracy in differentiating moderate-severe from mild fibrostenosis (area under the receiver operating characteristic [ROC] curve [AUC] = 0.799; p = 0.000). ROC analysis in the retrospective cohort identified a threshold MCFI of > 3 which accurately differentiated fibrostenosis severity in the prospective cohort [AUC = 0.756; p = 0.018]. An excellent correlation was shown between MCFI and the extent of fat wrapping in specimens in the prospective cohort [r = 0.840, p = 0.000]. Neither visceral to subcutaneous fat area ratio nor fibrofatty proliferation score correlated well with the degree of intestinal fibrosis.
MCFI can accurately characterize the extent of mesenteric fat wrapping in surgical specimens. It may become another non-invasive measure of CD fibrostenosis.</description><identifier>ISSN: 1873-9946</identifier><identifier>EISSN: 1876-4479</identifier><identifier>DOI: 10.1093/ecco-jcc/jjab005</identifier><identifier>PMID: 33411893</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Adipose Tissue - diagnostic imaging ; Adipose Tissue - pathology ; Adult ; Constriction, Pathologic - diagnostic imaging ; Constriction, Pathologic - pathology ; Crohn Disease - diagnostic imaging ; Crohn Disease - pathology ; Cross-Sectional Studies ; Female ; Fibrosis - diagnostic imaging ; Fibrosis - pathology ; Humans ; Male ; Original ; Prospective Studies ; Retrospective Studies ; Severity of Illness Index ; Tomography, X-Ray Computed - methods</subject><ispartof>Journal of Crohn's and colitis, 2021-07, Vol.15 (7), p.1161-1173</ispartof><rights>The Author(s) 2021. Published by Oxford University Press on behalf of European Crohn’s and Colitis Organisation. All rights reserved. For permissions, please email: journals.permissions@oup.com.</rights><rights>The Author(s) 2021. Published by Oxford University Press on behalf of European Crohn’s and Colitis Organisation. All rights reserved. For permissions, please email: journals.permissions@oup.com 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c396t-647395b374f656c5f5f35f6dbfe31ed61cbd634cdd3f358df10fc29107300a943</citedby><cites>FETCH-LOGICAL-c396t-647395b374f656c5f5f35f6dbfe31ed61cbd634cdd3f358df10fc29107300a943</cites><orcidid>0000-0002-7476-2644</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33411893$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Xue-Hua</creatorcontrib><creatorcontrib>Feng, Shi-Ting</creatorcontrib><creatorcontrib>Cao, Qing-Hua</creatorcontrib><creatorcontrib>Coffey, J Calvin</creatorcontrib><creatorcontrib>Baker, Mark E</creatorcontrib><creatorcontrib>Huang, Li</creatorcontrib><creatorcontrib>Fang, Zhuang-Nian</creatorcontrib><creatorcontrib>Qiu, Yun</creatorcontrib><creatorcontrib>Lu, Bao-Lan</creatorcontrib><creatorcontrib>Chen, Zhi-Hui</creatorcontrib><creatorcontrib>Li, Yi</creatorcontrib><creatorcontrib>Bettenworth, Dominik</creatorcontrib><creatorcontrib>Iacucci, Marietta</creatorcontrib><creatorcontrib>Sun, Can-Hui</creatorcontrib><creatorcontrib>Ghosh, Subrata</creatorcontrib><creatorcontrib>Rieder, Florian</creatorcontrib><creatorcontrib>Chen, Min-Hu</creatorcontrib><creatorcontrib>Li, Zi-Ping</creatorcontrib><creatorcontrib>Mao, Ren</creatorcontrib><title>Degree of Creeping Fat Assessed by Computed Tomography Enterography is Associated with Intestinal Fibrotic Stricture in Patients with Crohn's Disease: A Potentially Novel Mesenteric Creeping Fat Index</title><title>Journal of Crohn's and colitis</title><addtitle>J Crohns Colitis</addtitle><description>Emerging evidence points to a link between creeping fat and the pathogenesis of Crohn's disease [CD]. Non-invasive assessment of the severity of creeping fat on cross-sectional imaging modality has seldom been investigated. This study aimed to develop and characterize a novel mesenteric creeping fat index [MCFI] based on computed tomography [CT] in CD patients.
MCFI was developed based on vascular findings on CT in a retrospective cohort [n = 91] and validated in a prospective cohort [n = 30]. The severity of creeping fat was graded based on the extent to which mesenteric fat extended around the intestinal circumference using the vessels in the fat as a marker. The accuracy of MCFI was assessed by comparing it with the degree of creeping fat observed in surgical specimens. The relationship between MCFI and fibrostenosis was characterized by determining if these correlated. The accuracy of MCFI was compared with other radiographic indices [i.e. visceral to subcutaneous fat area ratio and fibrofatty proliferation score].
In the retrospective cohort, MCFI had moderate accuracy in differentiating moderate-severe from mild fibrostenosis (area under the receiver operating characteristic [ROC] curve [AUC] = 0.799; p = 0.000). ROC analysis in the retrospective cohort identified a threshold MCFI of > 3 which accurately differentiated fibrostenosis severity in the prospective cohort [AUC = 0.756; p = 0.018]. An excellent correlation was shown between MCFI and the extent of fat wrapping in specimens in the prospective cohort [r = 0.840, p = 0.000]. Neither visceral to subcutaneous fat area ratio nor fibrofatty proliferation score correlated well with the degree of intestinal fibrosis.
MCFI can accurately characterize the extent of mesenteric fat wrapping in surgical specimens. It may become another non-invasive measure of CD fibrostenosis.</description><subject>Adipose Tissue - diagnostic imaging</subject><subject>Adipose Tissue - pathology</subject><subject>Adult</subject><subject>Constriction, Pathologic - diagnostic imaging</subject><subject>Constriction, Pathologic - pathology</subject><subject>Crohn Disease - diagnostic imaging</subject><subject>Crohn Disease - pathology</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Fibrosis - diagnostic imaging</subject><subject>Fibrosis - pathology</subject><subject>Humans</subject><subject>Male</subject><subject>Original</subject><subject>Prospective Studies</subject><subject>Retrospective Studies</subject><subject>Severity of Illness Index</subject><subject>Tomography, X-Ray Computed - methods</subject><issn>1873-9946</issn><issn>1876-4479</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVUsFu1DAUtBCIloU7J-QbXELttRPHHJBWaRdWKlCJcrYc52XXqyQOtlPYP-SzcNhtRSVLz9bMmzfyG4ReU_KeEskuwBiX7Y252O91TUj-BJ3TUhQZ50I-_XdnmZS8OEMvQtgngsxF-RydMcYpLSU7R38uYesBsGtxlepohy1e64hXIUA6Da4PuHL9OMV0v3W923o97g74aojg7x82zHxnrJ5Zv2zc4U3CQ7SD7vDa1t5Fa_D36K2JkwdsB3yjo4UhhiO98m43vA340gbQAT7gFb5xMeFWd90Bf3V30OEvEGAem6Qeed0MDfx-iZ61ugvw6lQX6Mf66rb6nF1_-7SpVteZYbKIWcEFk3nNBG-LvDB5m7csb4umboFRaApq6qZg3DQNS0DZtJS0ZikpEYwQLTlboI9H3XGqe2hMcuR1p0Zve-0PymmrHiOD3amtu1MlXwpBWRJ4dxLw7ueUPkn1NhjoOj2Am4JacpGcCZ52t0DkSDXeheChfRhDiZoDoOYAqBQAdQpAannzv72HhvuNs7-djLTu</recordid><startdate>20210705</startdate><enddate>20210705</enddate><creator>Li, Xue-Hua</creator><creator>Feng, Shi-Ting</creator><creator>Cao, Qing-Hua</creator><creator>Coffey, J Calvin</creator><creator>Baker, Mark E</creator><creator>Huang, Li</creator><creator>Fang, Zhuang-Nian</creator><creator>Qiu, Yun</creator><creator>Lu, Bao-Lan</creator><creator>Chen, Zhi-Hui</creator><creator>Li, Yi</creator><creator>Bettenworth, Dominik</creator><creator>Iacucci, Marietta</creator><creator>Sun, Can-Hui</creator><creator>Ghosh, Subrata</creator><creator>Rieder, Florian</creator><creator>Chen, Min-Hu</creator><creator>Li, Zi-Ping</creator><creator>Mao, Ren</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-7476-2644</orcidid></search><sort><creationdate>20210705</creationdate><title>Degree of Creeping Fat Assessed by Computed Tomography Enterography is Associated with Intestinal Fibrotic Stricture in Patients with Crohn's Disease: A Potentially Novel Mesenteric Creeping Fat Index</title><author>Li, Xue-Hua ; Feng, Shi-Ting ; Cao, Qing-Hua ; Coffey, J Calvin ; Baker, Mark E ; Huang, Li ; Fang, Zhuang-Nian ; Qiu, Yun ; Lu, Bao-Lan ; Chen, Zhi-Hui ; Li, Yi ; Bettenworth, Dominik ; Iacucci, Marietta ; Sun, Can-Hui ; Ghosh, Subrata ; Rieder, Florian ; Chen, Min-Hu ; Li, Zi-Ping ; Mao, Ren</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c396t-647395b374f656c5f5f35f6dbfe31ed61cbd634cdd3f358df10fc29107300a943</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adipose Tissue - diagnostic imaging</topic><topic>Adipose Tissue - pathology</topic><topic>Adult</topic><topic>Constriction, Pathologic - diagnostic imaging</topic><topic>Constriction, Pathologic - pathology</topic><topic>Crohn Disease - diagnostic imaging</topic><topic>Crohn Disease - pathology</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>Fibrosis - diagnostic imaging</topic><topic>Fibrosis - pathology</topic><topic>Humans</topic><topic>Male</topic><topic>Original</topic><topic>Prospective Studies</topic><topic>Retrospective Studies</topic><topic>Severity of Illness Index</topic><topic>Tomography, X-Ray Computed - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Xue-Hua</creatorcontrib><creatorcontrib>Feng, Shi-Ting</creatorcontrib><creatorcontrib>Cao, Qing-Hua</creatorcontrib><creatorcontrib>Coffey, J Calvin</creatorcontrib><creatorcontrib>Baker, Mark E</creatorcontrib><creatorcontrib>Huang, Li</creatorcontrib><creatorcontrib>Fang, Zhuang-Nian</creatorcontrib><creatorcontrib>Qiu, Yun</creatorcontrib><creatorcontrib>Lu, Bao-Lan</creatorcontrib><creatorcontrib>Chen, Zhi-Hui</creatorcontrib><creatorcontrib>Li, Yi</creatorcontrib><creatorcontrib>Bettenworth, Dominik</creatorcontrib><creatorcontrib>Iacucci, Marietta</creatorcontrib><creatorcontrib>Sun, Can-Hui</creatorcontrib><creatorcontrib>Ghosh, Subrata</creatorcontrib><creatorcontrib>Rieder, Florian</creatorcontrib><creatorcontrib>Chen, Min-Hu</creatorcontrib><creatorcontrib>Li, Zi-Ping</creatorcontrib><creatorcontrib>Mao, Ren</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of Crohn's and colitis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Xue-Hua</au><au>Feng, Shi-Ting</au><au>Cao, Qing-Hua</au><au>Coffey, J Calvin</au><au>Baker, Mark E</au><au>Huang, Li</au><au>Fang, Zhuang-Nian</au><au>Qiu, Yun</au><au>Lu, Bao-Lan</au><au>Chen, Zhi-Hui</au><au>Li, Yi</au><au>Bettenworth, Dominik</au><au>Iacucci, Marietta</au><au>Sun, Can-Hui</au><au>Ghosh, Subrata</au><au>Rieder, Florian</au><au>Chen, Min-Hu</au><au>Li, Zi-Ping</au><au>Mao, Ren</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Degree of Creeping Fat Assessed by Computed Tomography Enterography is Associated with Intestinal Fibrotic Stricture in Patients with Crohn's Disease: A Potentially Novel Mesenteric Creeping Fat Index</atitle><jtitle>Journal of Crohn's and colitis</jtitle><addtitle>J Crohns Colitis</addtitle><date>2021-07-05</date><risdate>2021</risdate><volume>15</volume><issue>7</issue><spage>1161</spage><epage>1173</epage><pages>1161-1173</pages><issn>1873-9946</issn><eissn>1876-4479</eissn><abstract>Emerging evidence points to a link between creeping fat and the pathogenesis of Crohn's disease [CD]. Non-invasive assessment of the severity of creeping fat on cross-sectional imaging modality has seldom been investigated. This study aimed to develop and characterize a novel mesenteric creeping fat index [MCFI] based on computed tomography [CT] in CD patients.
MCFI was developed based on vascular findings on CT in a retrospective cohort [n = 91] and validated in a prospective cohort [n = 30]. The severity of creeping fat was graded based on the extent to which mesenteric fat extended around the intestinal circumference using the vessels in the fat as a marker. The accuracy of MCFI was assessed by comparing it with the degree of creeping fat observed in surgical specimens. The relationship between MCFI and fibrostenosis was characterized by determining if these correlated. The accuracy of MCFI was compared with other radiographic indices [i.e. visceral to subcutaneous fat area ratio and fibrofatty proliferation score].
In the retrospective cohort, MCFI had moderate accuracy in differentiating moderate-severe from mild fibrostenosis (area under the receiver operating characteristic [ROC] curve [AUC] = 0.799; p = 0.000). ROC analysis in the retrospective cohort identified a threshold MCFI of > 3 which accurately differentiated fibrostenosis severity in the prospective cohort [AUC = 0.756; p = 0.018]. An excellent correlation was shown between MCFI and the extent of fat wrapping in specimens in the prospective cohort [r = 0.840, p = 0.000]. Neither visceral to subcutaneous fat area ratio nor fibrofatty proliferation score correlated well with the degree of intestinal fibrosis.
MCFI can accurately characterize the extent of mesenteric fat wrapping in surgical specimens. It may become another non-invasive measure of CD fibrostenosis.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>33411893</pmid><doi>10.1093/ecco-jcc/jjab005</doi><tpages>13</tpages><orcidid>https://orcid.org/0000-0002-7476-2644</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1873-9946 |
| ispartof | Journal of Crohn's and colitis, 2021-07, Vol.15 (7), p.1161-1173 |
| issn | 1873-9946 1876-4479 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8427713 |
| source | MEDLINE; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection |
| subjects | Adipose Tissue - diagnostic imaging Adipose Tissue - pathology Adult Constriction, Pathologic - diagnostic imaging Constriction, Pathologic - pathology Crohn Disease - diagnostic imaging Crohn Disease - pathology Cross-Sectional Studies Female Fibrosis - diagnostic imaging Fibrosis - pathology Humans Male Original Prospective Studies Retrospective Studies Severity of Illness Index Tomography, X-Ray Computed - methods |
| title | Degree of Creeping Fat Assessed by Computed Tomography Enterography is Associated with Intestinal Fibrotic Stricture in Patients with Crohn's Disease: A Potentially Novel Mesenteric Creeping Fat Index |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-26T16%3A33%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Degree%20of%20Creeping%20Fat%20Assessed%20by%20Computed%20Tomography%20Enterography%20is%20Associated%20with%20Intestinal%20Fibrotic%20Stricture%20in%20Patients%20with%20Crohn's%20Disease:%20A%20Potentially%20Novel%20Mesenteric%20Creeping%20Fat%20Index&rft.jtitle=Journal%20of%20Crohn's%20and%20colitis&rft.au=Li,%20Xue-Hua&rft.date=2021-07-05&rft.volume=15&rft.issue=7&rft.spage=1161&rft.epage=1173&rft.pages=1161-1173&rft.issn=1873-9946&rft.eissn=1876-4479&rft_id=info:doi/10.1093/ecco-jcc/jjab005&rft_dat=%3Cproquest_pubme%3E2476567487%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2476567487&rft_id=info:pmid/33411893&rfr_iscdi=true |