The 5-Ketofructose Reductase of Gluconobacter sp. Strain CHM43 Is a Novel Class in the Shikimate Dehydrogenase Family

sp. strain CHM43 oxidizes mannitol to fructose and then oxidizes fructose to 5-keto-d-fructose (5KF) in the periplasmic space. Since NADPH-dependent 5KF reductase was found in the soluble fraction of spp., 5KF might be transported into the cytoplasm and metabolized. Here, we identified the gene as t...

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Veröffentlicht in:	Journal of bacteriology 2021-09, Vol.203 (19), p.e0055820-e0055820
Hauptverfasser:	Nguyen, Thuy Minh, Goto, Masaru, Noda, Shohei, Matsutani, Minenosuke, Hodoya, Yuki, Kataoka, Naoya, Adachi, Osao, Matsushita, Kazunobu, Yakushi, Toshiharu
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Bacterial Proteins - genetics Bacterial Proteins - metabolism Bacteriology Binding sites Carbohydrate Dehydrogenases - classification Carbohydrate Dehydrogenases - genetics Carbohydrate Dehydrogenases - metabolism Crystal structure Cytoplasm Dehydrogenase Dehydrogenases Fructose Gene Expression Regulation, Bacterial Gene Expression Regulation, Enzymologic Genetics and Molecular Biology Gluconobacter - enzymology Gluconobacter - genetics Gluconobacter - metabolism Mannitol Models, Molecular NADP Oxidation Periplasmic space Phylogeny Protein Conformation Reductase Reductases Research Article Shikimate dehydrogenase Substrates
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