Cellular feedback dynamics and multilevel regulation driven by the hippo pathway

The Hippo pathway is a dynamic cellular signalling nexus that regulates differentiation and controls cell proliferation and death. If the Hippo pathway is not precisely regulated, the functionality of the upstream kinase module is impaired, which increases nuclear localisation and activity of the ce...

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Veröffentlicht in:	Biochemical Society transactions 2021-08, Vol.49 (4), p.1515-1527
Hauptverfasser:	Park, Jiwon, Hansen, Carsten Gram
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Cycle, Growth & Proliferation Cell Homeostasis & Autophagy Cell Migration, Adhesion & Morphology Cell Movement Feedback Hippo Signaling Pathway Humans Male Mitosis Molecular Bases of Health & Disease Review Signaling
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