Histone deacetylase inhibitors enhance estrogen receptor beta expression and augment agonist-mediated tumor suppression in glioblastoma

Abstract Background Glioblastomas (GBMs) are the most lethal primary brain tumors. Estrogen receptor β (ESR2/ERβ) function as a tumor suppressor in GBM, however, ERβ expression is commonly suppressed during glioma progression. In this study, we examined whether drugs that reverse epigenetic modifica...

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Veröffentlicht in:	Neuro-oncology advances 2021-01, Vol.3 (1), p.vdab099-vdab099
Hauptverfasser:	Pratap, Uday P, Sareddy, Gangadhara R, Liu, Zexuan, Venkata, Prabhakar Pitta, Liu, Junhao, Tang, Weiwei, Altwegg, Kristin A, Ebrahimi, Behnam, Li, Xiaonan, Tekmal, Rajeshwar R, Viswanadhapalli, Suryavathi, McHardy, Stanton, Brenner, Andrew J, Vadlamudi, Ratna K
Format:	Artikel
Sprache:	eng
Schlagworte:	Basic and Translational Investigations
Online-Zugang:	Volltext
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