Cholestatic liver disease: Practice guidelines from the Saudi Association for the Study of Liver diseases and Transplantation

Cholestatic liver diseases (CLDs) are a group of diseases characterized by jaundice and cholestasis as the main presentation with different complications, which have considerable impact on the liver and can lead to end-stage liver disease, cirrhosis, and liver-related complications. In the last few...

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Veröffentlicht in:Saudi journal of gastroenterology 2021-07, Vol.27 (7), p.1-26
Hauptverfasser: Mawardi, Mohammad, Alalwan, Abduljaleel, Fallatah, Hind, Abaalkhail, Faisal, Hasosah, Mohammed, Shagrani, Mohammad, Alghamdi, Mohammed, Alghamdi, Abdullah
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container_end_page 26
container_issue 7
container_start_page 1
container_title Saudi journal of gastroenterology
container_volume 27
creator Mawardi, Mohammad
Alalwan, Abduljaleel
Fallatah, Hind
Abaalkhail, Faisal
Hasosah, Mohammed
Shagrani, Mohammad
Alghamdi, Mohammed
Alghamdi, Abdullah
description Cholestatic liver diseases (CLDs) are a group of diseases characterized by jaundice and cholestasis as the main presentation with different complications, which have considerable impact on the liver and can lead to end-stage liver disease, cirrhosis, and liver-related complications. In the last few years, tremendous progress has been made in understanding the pathophysiology, diagnosis, and treatment of patients with these conditions. However, several aspects related to the management of CLDs remain deficient and unclear. Due to the lack of recommendations that can help in the management, treatment of those conditions, the Saudi Association for the Study of Liver diseases and Transplantation (SASLT) has created a task force group to develop guidelines related to CLDs management in order to provide a standard of care for patients in need. These guidelines provide general guidance for health care professionals to optimize medical care for patients with CLDs for both adult and pediatric populations, in association with clinical judgments to be considered on a case-by-case basis. These guidelines describe common CLDs in Saudi Arabia, with recommendations on the best approach for diagnosis and management of different diseases based on the Grading of Recommendation Assessment (GRADE), combined with a level of evidence available in the literature.
doi_str_mv 10.4103/sjg.sjg_112_21
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subjects Care and treatment
Clinical Practice Guidelines
Evidence-based medicine
Gastroenterology
Liver
Liver cirrhosis
Liver diseases
Medical diagnosis
Medical research
Medical treatment
Medicine, Experimental
Pathophysiology
Practice guidelines (Medicine)
Transplantation
title Cholestatic liver disease: Practice guidelines from the Saudi Association for the Study of Liver diseases and Transplantation
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