Cholestatic liver disease: Practice guidelines from the Saudi Association for the Study of Liver diseases and Transplantation
Cholestatic liver diseases (CLDs) are a group of diseases characterized by jaundice and cholestasis as the main presentation with different complications, which have considerable impact on the liver and can lead to end-stage liver disease, cirrhosis, and liver-related complications. In the last few...
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Veröffentlicht in: | Saudi journal of gastroenterology 2021-07, Vol.27 (7), p.1-26 |
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container_title | Saudi journal of gastroenterology |
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creator | Mawardi, Mohammad Alalwan, Abduljaleel Fallatah, Hind Abaalkhail, Faisal Hasosah, Mohammed Shagrani, Mohammad Alghamdi, Mohammed Alghamdi, Abdullah |
description | Cholestatic liver diseases (CLDs) are a group of diseases characterized by jaundice and cholestasis as the main presentation with different complications, which have considerable impact on the liver and can lead to end-stage liver disease, cirrhosis, and liver-related complications. In the last few years, tremendous progress has been made in understanding the pathophysiology, diagnosis, and treatment of patients with these conditions. However, several aspects related to the management of CLDs remain deficient and unclear. Due to the lack of recommendations that can help in the management, treatment of those conditions, the Saudi Association for the Study of Liver diseases and Transplantation (SASLT) has created a task force group to develop guidelines related to CLDs management in order to provide a standard of care for patients in need. These guidelines provide general guidance for health care professionals to optimize medical care for patients with CLDs for both adult and pediatric populations, in association with clinical judgments to be considered on a case-by-case basis. These guidelines describe common CLDs in Saudi Arabia, with recommendations on the best approach for diagnosis and management of different diseases based on the Grading of Recommendation Assessment (GRADE), combined with a level of evidence available in the literature. |
doi_str_mv | 10.4103/sjg.sjg_112_21 |
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In the last few years, tremendous progress has been made in understanding the pathophysiology, diagnosis, and treatment of patients with these conditions. However, several aspects related to the management of CLDs remain deficient and unclear. Due to the lack of recommendations that can help in the management, treatment of those conditions, the Saudi Association for the Study of Liver diseases and Transplantation (SASLT) has created a task force group to develop guidelines related to CLDs management in order to provide a standard of care for patients in need. These guidelines provide general guidance for health care professionals to optimize medical care for patients with CLDs for both adult and pediatric populations, in association with clinical judgments to be considered on a case-by-case basis. These guidelines describe common CLDs in Saudi Arabia, with recommendations on the best approach for diagnosis and management of different diseases based on the Grading of Recommendation Assessment (GRADE), combined with a level of evidence available in the literature.</description><identifier>ISSN: 1319-3767</identifier><identifier>EISSN: 1998-4049</identifier><identifier>DOI: 10.4103/sjg.sjg_112_21</identifier><language>eng</language><publisher>Riyadh: Wolters Kluwer India Pvt. Ltd</publisher><subject>Care and treatment ; Clinical Practice Guidelines ; Evidence-based medicine ; Gastroenterology ; Liver ; Liver cirrhosis ; Liver diseases ; Medical diagnosis ; Medical research ; Medical treatment ; Medicine, Experimental ; Pathophysiology ; Practice guidelines (Medicine) ; Transplantation</subject><ispartof>Saudi journal of gastroenterology, 2021-07, Vol.27 (7), p.1-26</ispartof><rights>COPYRIGHT 2021 Medknow Publications and Media Pvt. Ltd.</rights><rights>2021. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright: © 2021 Saudi Journal of Gastroenterology 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c444a-b22fc74922f432ed0275847ae6d1a159f3fb42a5f53f51b5669c98281d00fa9f3</citedby><cites>FETCH-LOGICAL-c444a-b22fc74922f432ed0275847ae6d1a159f3fb42a5f53f51b5669c98281d00fa9f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411950/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8411950/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27435,27901,27902,53766,53768</link.rule.ids></links><search><creatorcontrib>Mawardi, Mohammad</creatorcontrib><creatorcontrib>Alalwan, Abduljaleel</creatorcontrib><creatorcontrib>Fallatah, Hind</creatorcontrib><creatorcontrib>Abaalkhail, Faisal</creatorcontrib><creatorcontrib>Hasosah, Mohammed</creatorcontrib><creatorcontrib>Shagrani, Mohammad</creatorcontrib><creatorcontrib>Alghamdi, Mohammed</creatorcontrib><creatorcontrib>Alghamdi, Abdullah</creatorcontrib><title>Cholestatic liver disease: Practice guidelines from the Saudi Association for the Study of Liver diseases and Transplantation</title><title>Saudi journal of gastroenterology</title><description>Cholestatic liver diseases (CLDs) are a group of diseases characterized by jaundice and cholestasis as the main presentation with different complications, which have considerable impact on the liver and can lead to end-stage liver disease, cirrhosis, and liver-related complications. In the last few years, tremendous progress has been made in understanding the pathophysiology, diagnosis, and treatment of patients with these conditions. However, several aspects related to the management of CLDs remain deficient and unclear. Due to the lack of recommendations that can help in the management, treatment of those conditions, the Saudi Association for the Study of Liver diseases and Transplantation (SASLT) has created a task force group to develop guidelines related to CLDs management in order to provide a standard of care for patients in need. These guidelines provide general guidance for health care professionals to optimize medical care for patients with CLDs for both adult and pediatric populations, in association with clinical judgments to be considered on a case-by-case basis. These guidelines describe common CLDs in Saudi Arabia, with recommendations on the best approach for diagnosis and management of different diseases based on the Grading of Recommendation Assessment (GRADE), combined with a level of evidence available in the literature.</description><subject>Care and treatment</subject><subject>Clinical Practice Guidelines</subject><subject>Evidence-based medicine</subject><subject>Gastroenterology</subject><subject>Liver</subject><subject>Liver cirrhosis</subject><subject>Liver diseases</subject><subject>Medical diagnosis</subject><subject>Medical research</subject><subject>Medical treatment</subject><subject>Medicine, Experimental</subject><subject>Pathophysiology</subject><subject>Practice guidelines (Medicine)</subject><subject>Transplantation</subject><issn>1319-3767</issn><issn>1998-4049</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp1Uk2LFDEQbUTBdfXqOeC5x3x2dzwIw-AXDCi4nkMmqcxkNp2MSfcOe_C_m3FXR2ElhCrq1XtU5aVpXhK84ASz12W_XdSrCKGKkkfNBZFyaDnm8nHNGZEt67v-afOslD3GgjDBLpofq10KUCY9eYOCv4GMrC-gC7xBX7I2tQxoO3sLwUcoyOU0omkH6KuerUfLUpLxlZwicinfIdNsb1FyaP23XEE6WnSVdSyHoOP0i_O8eeJ0KPDiPl42396_u1p9bNefP3xaLdet4ZzrdkOpMz2XNXBGwWLai4H3GjpLNBHSMbfhVAsnmBNkI7pOGjnQgViMna7wZfP2Tvcwb0awBuKUdVCH7Eedb1XSXv2LRL9T23SjBk6IFLgKvLoXyOn7XN9L7dOcY51ZUSF6Rnk3kHPXVgdQPrpUxczoi1HLrsccd4SftBYPdNVjYfQmRXC-1h8imJxKyeD-DE6wOlmvTrafrT-ve0xhglyuw3yErOp-1zEd_8NSRP3-C-wnflC65w</recordid><startdate>20210701</startdate><enddate>20210701</enddate><creator>Mawardi, Mohammad</creator><creator>Alalwan, Abduljaleel</creator><creator>Fallatah, Hind</creator><creator>Abaalkhail, Faisal</creator><creator>Hasosah, Mohammed</creator><creator>Shagrani, Mohammad</creator><creator>Alghamdi, Mohammed</creator><creator>Alghamdi, Abdullah</creator><general>Wolters Kluwer India Pvt. 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source | Medknow Open Access Medical Journals; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; PubMed Central Open Access |
subjects | Care and treatment Clinical Practice Guidelines Evidence-based medicine Gastroenterology Liver Liver cirrhosis Liver diseases Medical diagnosis Medical research Medical treatment Medicine, Experimental Pathophysiology Practice guidelines (Medicine) Transplantation |
title | Cholestatic liver disease: Practice guidelines from the Saudi Association for the Study of Liver diseases and Transplantation |
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