CEA, CA19-9, circulating DNA and circulating tumour cell kinetics in patients treated for metastatic colorectal cancer (mCRC)

Background We previously reported that CEA kinetics are a marker of progressive disease (PD) in metastatic colorectal cancer (mCRC). This study was specifically designed to confirm CEA kinetics for predicting PD and to evaluate CA19-9, cell-free DNA (cfDNA), circulating tumour DNA (ctDNA) and circul...

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Veröffentlicht in:	British journal of cancer 2021-08, Vol.125 (5), p.725-733
Hauptverfasser:	Sefrioui, David, Beaussire, Ludivine, Gillibert, André, Blanchard, France, Toure, Emmanuel, Bazille, Céline, Perdrix, Anne, Ziegler, Frédéric, Gangloff, Alice, Hassine, Mélanie, Elie, Caroline, Bignon, Anne-Laure, Parzy, Aurélie, Gomez, Philippe, Thill, Caroline, Clatot, Florian, Sabourin, Jean-Christophe, Frebourg, Thierry, Benichou, Jacques, Bouhier-Leporrier, Karine, Gallais, Marie-Pierre, Sarafan-Vasseur, Nasrin, Michel, Pierre, Di Fiore, Frédéric
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/721 631/67/1504/1885/1393 Adult Aged Aged, 80 and over Antigens, Tumor-Associated, Carbohydrate - metabolism Biomedical and Life Sciences Biomedicine Cancer Research Carcinoembryonic Antigen - metabolism Chemotherapy Circulating Tumor DNA - genetics Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - drug therapy Colorectal Neoplasms - genetics Colorectal Neoplasms - pathology Deoxyribonucleic acid DNA Drug Resistance Epidemiology Female Gene Expression Regulation, Neoplastic Human health and pathology Humans Life Sciences Male Metastases Metastasis Middle Aged Molecular Medicine Multivariate analysis Neoplasm Metastasis Neoplastic Cells, Circulating - drug effects Neoplastic Cells, Circulating - metabolism Oncology Patients Prospective Studies Survival Analysis Tissues and Organs Tumors Up-Regulation
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