Longitudinal analysis of individual cfDNA methylome patterns in metastatic prostate cancer

Disease progression and therapeutic resistance are hallmarks of advanced stage prostate cancer (PCa), which remains a major cause of cancer-related mortality around the world. Longitudinal studies, coupled with the use of liquid biopsies, offer a potentially new and minimally invasive platform to st...

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Veröffentlicht in:	Clinical epigenetics 2021-12, Vol.13 (1), p.168-168, Article 168
Hauptverfasser:	Silva, Romina, Moran, Bruce, Baird, Anne-Marie, O'Rourke, Colm J, Finn, Stephen P, McDermott, Ray, Watson, William, Gallagher, William M, Brennan, Donal J, Perry, Antoinette S
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Analysis Biomarkers, Tumor - genetics Biopsy Cancer Cancer therapies Care and treatment Cluster analysis CpG islands Deoxyribonucleic acid Development and progression Disease resistance DNA DNA methylation DNA Methylation - genetics DNA probes Epidemiology Epigenesis, Genetic Epigenetics Epigenome Gene Expression Regulation, Neoplastic - genetics Genes Health aspects Humans Immune response Investigations Ireland Longitudinal Studies Male Medical colleges Metastases Metastasis Methylation Middle Aged Mortality Neoplasm Metastasis - genetics Oncology, Experimental Patients Principal components analysis Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - physiopathology Tumors
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