Quyu Shengxin Decoction Alleviates DSS-Induced Ulcerative Colitis in Mice by Suppressing RIP1/RIP3/NLRP3 Signalling

Purpose. To study the therapeutic effect of Quyu (QY) Shengxin (SX) decoction (QYSXD) in mice with dextran sulfate sodium- (DSS-) induced ulcerative colitis and to investigate the effects of QYSXD on the regulation of the receptor-interacting protein kinase 1 (RIP1)/receptor-interacting protein kina...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2021, Vol.2021, p.6682233-14
Hauptverfasser:	Wu, Chuang, Yang, Haojie, Han, Changpeng, Wang, Qingming, Zhang, Haiyan, Huang, Ting, Mao, Wenjing, Tang, Cheng, Zhao, Wenjun, Zhu, Zhiming, Xu, Jing, Yang, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Caspase-1 Chinese medicine Colon Dextran Dextran sulfate Drinking water Dynamin Enzyme-linked immunosorbent assay Gene expression IL-1β Immunofluorescence Inflammation Inflammatory bowel disease Interleukin 18 Interleukin 8 Kinases Mitochondria Mucosa Oligomerization Pathogenesis Protein kinase Proteinase Proteins Pyrin protein Reactive oxygen species Reverse transcription Signal transduction Tumor necrosis factor-TNF Ulcerative colitis Western blotting
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