Personalizing Medicine and Technologies to Address the Experiences and Needs of People with Multiple Sclerosis

There is enormous variation in the manifestations of disease experienced by people with multiple sclerosis (PwMS). While this variation makes personalized medicine an attractive goal, there are many challenges to be overcome before this opportunity can be realized. Personalized medicine often focuse...

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Veröffentlicht in:Journal of personalized medicine 2021-08, Vol.11 (8), p.791
Hauptverfasser: Henschke, Adam, Desborough, Jane, Parkinson, Anne, Brunoro, Crystal, Fanning, Vanessa, Lueck, Christian, Brew-Sam, Nicola, Brüstle, Anne, Drew, Janet, Chisholm, Katrina, Elisha, Mark, Suominen, Hanna, Tricoli, Antonio, Phillips, Christine, Cook, Matthew
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container_issue 8
container_start_page 791
container_title Journal of personalized medicine
container_volume 11
creator Henschke, Adam
Desborough, Jane
Parkinson, Anne
Brunoro, Crystal
Fanning, Vanessa
Lueck, Christian
Brew-Sam, Nicola
Brüstle, Anne
Drew, Janet
Chisholm, Katrina
Elisha, Mark
Suominen, Hanna
Tricoli, Antonio
Phillips, Christine
Cook, Matthew
description There is enormous variation in the manifestations of disease experienced by people with multiple sclerosis (PwMS). While this variation makes personalized medicine an attractive goal, there are many challenges to be overcome before this opportunity can be realized. Personalized medicine often focuses on targeted therapies and detailed monitoring, but we also need to recognize that there will be variation in acceptance of these approaches by different PwMS. In other words, deep personalization of medicine will encompass targeted therapy, precision monitoring, tailored to variation in personal attitudes to these transformations in health care. In order to meet the promise of personalized medicine for MS, understanding the experiences of PwMS is necessary both to aid in the uptake of personalized medicine, and to ensure that personalized approaches to monitoring disease and treatment provide a net benefit to PwMS rather than placing additional burdens and stressors on them. Here, we describe recent research that identified five experiential themes for PwMS, and then interpret these themes according to the foundations of personalized medicine to provide a road map for implementation of personalized medicine solutions for PwMS.
doi_str_mv 10.3390/jpm11080791
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source PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; EZB-FREE-00999 freely available EZB journals; PubMed Central
subjects Artificial intelligence
Customization
Drugs
Genomes
Multiple sclerosis
Patients
Physiology
Precision medicine
Variation
title Personalizing Medicine and Technologies to Address the Experiences and Needs of People with Multiple Sclerosis
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