Personalizing Medicine and Technologies to Address the Experiences and Needs of People with Multiple Sclerosis
There is enormous variation in the manifestations of disease experienced by people with multiple sclerosis (PwMS). While this variation makes personalized medicine an attractive goal, there are many challenges to be overcome before this opportunity can be realized. Personalized medicine often focuse...
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Veröffentlicht in: | Journal of personalized medicine 2021-08, Vol.11 (8), p.791 |
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container_title | Journal of personalized medicine |
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creator | Henschke, Adam Desborough, Jane Parkinson, Anne Brunoro, Crystal Fanning, Vanessa Lueck, Christian Brew-Sam, Nicola Brüstle, Anne Drew, Janet Chisholm, Katrina Elisha, Mark Suominen, Hanna Tricoli, Antonio Phillips, Christine Cook, Matthew |
description | There is enormous variation in the manifestations of disease experienced by people with multiple sclerosis (PwMS). While this variation makes personalized medicine an attractive goal, there are many challenges to be overcome before this opportunity can be realized. Personalized medicine often focuses on targeted therapies and detailed monitoring, but we also need to recognize that there will be variation in acceptance of these approaches by different PwMS. In other words, deep personalization of medicine will encompass targeted therapy, precision monitoring, tailored to variation in personal attitudes to these transformations in health care. In order to meet the promise of personalized medicine for MS, understanding the experiences of PwMS is necessary both to aid in the uptake of personalized medicine, and to ensure that personalized approaches to monitoring disease and treatment provide a net benefit to PwMS rather than placing additional burdens and stressors on them. Here, we describe recent research that identified five experiential themes for PwMS, and then interpret these themes according to the foundations of personalized medicine to provide a road map for implementation of personalized medicine solutions for PwMS. |
doi_str_mv | 10.3390/jpm11080791 |
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While this variation makes personalized medicine an attractive goal, there are many challenges to be overcome before this opportunity can be realized. Personalized medicine often focuses on targeted therapies and detailed monitoring, but we also need to recognize that there will be variation in acceptance of these approaches by different PwMS. In other words, deep personalization of medicine will encompass targeted therapy, precision monitoring, tailored to variation in personal attitudes to these transformations in health care. In order to meet the promise of personalized medicine for MS, understanding the experiences of PwMS is necessary both to aid in the uptake of personalized medicine, and to ensure that personalized approaches to monitoring disease and treatment provide a net benefit to PwMS rather than placing additional burdens and stressors on them. Here, we describe recent research that identified five experiential themes for PwMS, and then interpret these themes according to the foundations of personalized medicine to provide a road map for implementation of personalized medicine solutions for PwMS.</description><identifier>ISSN: 2075-4426</identifier><identifier>EISSN: 2075-4426</identifier><identifier>DOI: 10.3390/jpm11080791</identifier><identifier>PMID: 34442434</identifier><language>eng</language><publisher>Basel: MDPI AG</publisher><subject>Artificial intelligence ; Customization ; Drugs ; Genomes ; Multiple sclerosis ; Patients ; Physiology ; Precision medicine ; Variation</subject><ispartof>Journal of personalized medicine, 2021-08, Vol.11 (8), p.791</ispartof><rights>2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 by the authors. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-a6f18a3490a733c22ab94ad76a9d1650b8d1e972f1955ee8090fa10cddf28cae3</citedby><cites>FETCH-LOGICAL-c386t-a6f18a3490a733c22ab94ad76a9d1650b8d1e972f1955ee8090fa10cddf28cae3</cites><orcidid>0000-0002-3842-5683 ; 0000-0001-9053-0707 ; 0000-0002-2956-0883</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401762/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401762/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids></links><search><creatorcontrib>Henschke, Adam</creatorcontrib><creatorcontrib>Desborough, Jane</creatorcontrib><creatorcontrib>Parkinson, Anne</creatorcontrib><creatorcontrib>Brunoro, Crystal</creatorcontrib><creatorcontrib>Fanning, Vanessa</creatorcontrib><creatorcontrib>Lueck, Christian</creatorcontrib><creatorcontrib>Brew-Sam, Nicola</creatorcontrib><creatorcontrib>Brüstle, Anne</creatorcontrib><creatorcontrib>Drew, Janet</creatorcontrib><creatorcontrib>Chisholm, Katrina</creatorcontrib><creatorcontrib>Elisha, Mark</creatorcontrib><creatorcontrib>Suominen, Hanna</creatorcontrib><creatorcontrib>Tricoli, Antonio</creatorcontrib><creatorcontrib>Phillips, Christine</creatorcontrib><creatorcontrib>Cook, Matthew</creatorcontrib><title>Personalizing Medicine and Technologies to Address the Experiences and Needs of People with Multiple Sclerosis</title><title>Journal of personalized medicine</title><description>There is enormous variation in the manifestations of disease experienced by people with multiple sclerosis (PwMS). 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subjects | Artificial intelligence Customization Drugs Genomes Multiple sclerosis Patients Physiology Precision medicine Variation |
title | Personalizing Medicine and Technologies to Address the Experiences and Needs of People with Multiple Sclerosis |
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