CD73 Promotes Tumor Progression in Patients with Esophageal Squamous Cell Carcinoma

Cluster of differentiation (CD)-73 plays pivotal roles in the regulation of immune reactions via the production of extracellular adenosine, and the overexpression of CD73 is associated with worse outcomes in several types of cancers. Here, we identified 167 esophageal squamous cell carcinoma (ESCC)...

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Veröffentlicht in:	Cancers 2021-08, Vol.13 (16), p.3982
Hauptverfasser:	Chen, Yen-Hao, Lu, Hung-I, Lo, Chien-Ming, Li, Shau-Hsuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Angiogenesis Antibodies Antigens Antitumor activity Apoptosis CD73 antigen Cell differentiation Cell interactions Cell migration Cell proliferation Chemotherapy Clinical outcomes E-cadherin Esophageal cancer Esophagus Extracellular matrix Immune system Immunosuppression Immunotherapy Lymphocytes T Medical prognosis Metastases Metastasis Patients Pembrolizumab Radiation therapy Squamous cell carcinoma Tumor cells Vimentin Western blotting
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