Adipsin-Dependent Secretion of Hepatocyte Growth Factor Regulates the Adipocyte-Cancer Stem Cell Interaction

Adipose tissue is a component of the tumor microenvironment and is involved in tumor progression. We have previously shown that adipokine adipsin (CFD) functions as an enhancer of tumor proliferation and cancer stem cell (CSC) properties in breast cancers. We established the Cfd-knockout (KO) mice a...

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Veröffentlicht in:	Cancers 2021-08, Vol.13 (16), p.4238
Hauptverfasser:	Mizuno, Masahiro, Khaledian, Behnoush, Maeda, Masao, Hayashi, Takanori, Mizuno, Seiya, Munetsuna, Eiji, Watanabe, Takashi, Kono, Seishi, Okada, Seiji, Suzuki, Motoshi, Takao, Shintaro, Minami, Hironobu, Asai, Naoya, Sugiyama, Fumihiro, Takahashi, Satoru, Shimono, Yohei
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipose tissue Breast cancer Cell culture Cell interactions Cell proliferation Cloning Hepatocyte growth factor Laboratories Metastases Patients Secretion Stem cell transplantation Stem cells Tumor microenvironment Xenografts
Online-Zugang:	Volltext
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