MET Mutation Is a Potential Therapeutic Target for Advanced Endometrial Cancer

An optimal therapeutic regimen for endometrial cancer with extra-uterine metastasis is unavailable. This study aims to improve our understanding of the genomic landscape of advanced endometrial cancer and identify potential therapeutic targets. The clinical and genomic profiles of 81 patients with s...

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Veröffentlicht in:	Cancers 2021-08, Vol.13 (16), p.4231
Hauptverfasser:	Yeh, Yu-Min, Wu, Pei-Ying, Lin, Peng-Chan, Su, Pei-Fang, Hsu, Ya-Ting, Hsu, Keng-Fu, Shen, Meng-Ru
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Bruton's tyrosine kinase c-Met protein Cancer therapies Chemoresistance Chemotherapy Cisplatin Clinical trials Endometrial cancer Endometrium Estrogens Genomes Genomics Hepatocyte growth factor Medical prognosis Medical research Metastases Metastasis Mutagenesis Mutation Patients Phosphorylation Protein-tyrosine kinase Proteins Survival Therapeutic applications Therapeutic targets Tumors Uterine cancer Uterus
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