T-CoV: a comprehensive portal of HLA-peptide interactions affected by SARS-CoV-2 mutations

Abstract Rapidly appearing SARS-CoV-2 mutations can affect T cell epitopes, which can help the virus to evade either CD8 or CD4 T-cell responses. We developed T-cell COVID-19 Atlas (T-CoV, https://t-cov.hse.ru) – the comprehensive web portal, which allows one to analyze how SARS-CoV-2 mutations alte...

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Veröffentlicht in:	Nucleic acids research 2022-01, Vol.50 (D1), p.D883-D887
Hauptverfasser:	Nersisyan, Stepan, Zhiyanov, Anton, Shkurnikov, Maxim, Tonevitsky, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Codon, Terminator COVID-19 - immunology COVID-19 - virology Database Issue Databases, Factual Epitopes, T-Lymphocyte - immunology HLA Antigens - genetics HLA Antigens - immunology HLA Antigens - metabolism HLA-B7 Antigen - immunology Host-Pathogen Interactions Humans India Mutation SARS-CoV-2 - genetics SARS-CoV-2 - pathogenicity United Kingdom Viral Proteins - genetics Viral Proteins - immunology
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