Elephant Genomes Reveal Accelerated Evolution in Mechanisms Underlying Disease Defenses

Disease susceptibility and resistance are important factors for the conservation of endangered species, including elephants. We analyzed pathology data from 26 zoos and report that Asian elephants have increased neoplasia and malignancy prevalence compared with African bush elephants. This is consis...

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Veröffentlicht in:	Molecular biology and evolution 2021-09, Vol.38 (9), p.3606-3620
Hauptverfasser:	Tollis, Marc, Ferris, Elliott, Campbell, Michael S, Harris, Valerie K, Rupp, Shawn M, Harrison, Tara M, Kiso, Wendy K, Schmitt, Dennis L, Garner, Michael M, Aktipis, Christina Athena, Maley, Carlo C, Boddy, Amy M, Yandell, Mark, Gregg, Christopher, Schiffman, Joshua D, Abegglen, Lisa M
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Anopheles Cancer Communicable diseases Discoveries Disease susceptibility Elephants - genetics Endangered Species Ethylenediaminetetraacetic acid Genes Genomes Genomics Herpesviridae - genetics Herpesviridae Infections - epidemiology Mediation Oncology, Experimental Protection and preservation Tuberculosis Tumor proteins Wildlife conservation Zoos
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