Methylomic Investigation of Problematic Adolescent Cannabis Use and Its Negative Mental Health Consequences

The impact of adolescent cannabis use is a pressing public health question owing to the high rates of use and links to negative outcomes. This study considered the association between problematic adolescent cannabis use and methylation. Using an enrichment-based sequencing approach, a methylome-wide...

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Veröffentlicht in:	Journal of the American Academy of Child and Adolescent Psychiatry 2021-12, Vol.60 (12), p.1524-1532
Hauptverfasser:	Clark, Shaunna L., Chan, Robin, Zhao, Min, Xie, Lin Y., Copeland, William E., Aberg, Karolina A., van den Oord, Edwin J.C.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adolescents Adults Age Blood Brain Cannabis Child development DNA Methylation Drug use Drug withdrawal Educational attainment Epigenetics Estimates Genes Genome-Wide Association Study Genomes Granulocytes Health status Humans Inflammation Information storage Intelligence Leukocytes (granulocytic) Lymphocytes B Lymphocytes T Marijuana Mental Health Monocytes Multiple Regression Analysis Psychosis Psychotic Disorders Public health Quality control substance use Variants
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