Postoperative severe visual impairment: surgical outcome of 165 patients with orbital tumours in the muscle cone
Objective This study aimed to evaluate the risk factors of postoperative severe vision impairment (PSVI) for a primary orbital tumour in the muscle cone. Methods A retrospective analysis of the patients who underwent orbitotomy for primary intraconal tumours at the Tianjin Medical University Eye Hos...
Gespeichert in:
| Veröffentlicht in: | Eye (London) 2021-09, Vol.35 (9), p.2535-2542 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2542 |
|---|---|
| container_issue | 9 |
| container_start_page | 2535 |
| container_title | Eye (London) |
| container_volume | 35 |
| creator | Jian, Tianming Sun, Fengyuan Wu, Tong Zhao, Liang Huang, Xiaoming Wang, Lina He, Yanjin Tang, Dongrun |
| description | Objective
This study aimed to evaluate the risk factors of postoperative severe vision impairment (PSVI) for a primary orbital tumour in the muscle cone.
Methods
A retrospective analysis of the patients who underwent orbitotomy for primary intraconal tumours at the Tianjin Medical University Eye Hospital from January 2010 to December 2015.
Results
A total of 165 cases of orbitotomy for primary orbital tumours in the muscle cone were included in the study. Postoperatively, 12 cases with vision acuity ≤20/400 or ≥4 rows of vision decline and without any corrected effect were analysed as PSVI, including no light perception (NLP) for 3 cases. The multivariate logistic regression indicated that the tumour in orbital apex (
P
= 0.048, OR = 4.912, 95% CI: 1.011–23.866), severe optic nerve displacement (
P
= 0.030, OR = 6.007, 95% CI: 1.184–30.473) and intraoperative tight adhesion (
P
= 0.003, OR = 12.031, 95% CI: 2.282–63.441) were the independent risk factors for PSVI.
Conclusions
The incidence of PSVI for the intraconal tumour was 7.3%, and the incidence of NLP was 1.8%. The tumour in orbital apex, severe optic nerve displacement and intraoperative tight adhesion were independent risk factors for PSVI. |
| doi_str_mv | 10.1038/s41433-020-01270-7 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8377043</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2562649291</sourcerecordid><originalsourceid>FETCH-LOGICAL-c451t-dc8525b4a33900ebf8e6cd15eee3be421c12f6558a77f49ff25a1a4d01a3ac713</originalsourceid><addsrcrecordid>eNp9kUtr3DAUhUVpaKbT_oGuBNl040Zv2V0EQugjEEgWKXQnZM31jIJtuXpMyb-P0gkN7SIrge53Dufeg9AHSj5RwtvTJKjgvCGMNIQyTRr9Cq2o0KqRQorXaEU6SRrG2M9j9DalO0LqUJM36Jhz2grRkRVabkLKYYFos98DTrCHCHjvU7Ej9tNifZxgzp9xKnHrXf0MJbswAQ4DpkripQorkPBvn3c4xN7nCuUyhRIT9jPOO8BTSW4E7MIM79DRYMcE75_eNfrx9cvtxffm6vrb5cX5VeOEpLnZuFYy2QvLeUcI9EMLym2oBADeg2DUUTYoKVur9SC6YWDSUis2hFpunaZ8jc4OvkvpJ9i4mjHa0SzRTzbem2C9-Xcy-53Zhr1peb1RvesafXwyiOFXgZTN5JODcbQzhJIME4popTslK3ryH3pXt5_reoZJxZToWPeYiB0oF0NKEYa_YSgxj4WaQ6GmFmr-FGp0FfGDKFV43kJ8tn5B9QBx_KSA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2562649291</pqid></control><display><type>article</type><title>Postoperative severe visual impairment: surgical outcome of 165 patients with orbital tumours in the muscle cone</title><source>Springer Nature - Complete Springer Journals</source><source>PubMed Central</source><creator>Jian, Tianming ; Sun, Fengyuan ; Wu, Tong ; Zhao, Liang ; Huang, Xiaoming ; Wang, Lina ; He, Yanjin ; Tang, Dongrun</creator><creatorcontrib>Jian, Tianming ; Sun, Fengyuan ; Wu, Tong ; Zhao, Liang ; Huang, Xiaoming ; Wang, Lina ; He, Yanjin ; Tang, Dongrun</creatorcontrib><description>Objective
This study aimed to evaluate the risk factors of postoperative severe vision impairment (PSVI) for a primary orbital tumour in the muscle cone.
Methods
A retrospective analysis of the patients who underwent orbitotomy for primary intraconal tumours at the Tianjin Medical University Eye Hospital from January 2010 to December 2015.
Results
A total of 165 cases of orbitotomy for primary orbital tumours in the muscle cone were included in the study. Postoperatively, 12 cases with vision acuity ≤20/400 or ≥4 rows of vision decline and without any corrected effect were analysed as PSVI, including no light perception (NLP) for 3 cases. The multivariate logistic regression indicated that the tumour in orbital apex (
P
= 0.048, OR = 4.912, 95% CI: 1.011–23.866), severe optic nerve displacement (
P
= 0.030, OR = 6.007, 95% CI: 1.184–30.473) and intraoperative tight adhesion (
P
= 0.003, OR = 12.031, 95% CI: 2.282–63.441) were the independent risk factors for PSVI.
Conclusions
The incidence of PSVI for the intraconal tumour was 7.3%, and the incidence of NLP was 1.8%. The tumour in orbital apex, severe optic nerve displacement and intraoperative tight adhesion were independent risk factors for PSVI.</description><identifier>ISSN: 0950-222X</identifier><identifier>EISSN: 1476-5454</identifier><identifier>DOI: 10.1038/s41433-020-01270-7</identifier><identifier>PMID: 33184490</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/499 ; 692/699/3161/3178 ; 692/700/565/545 ; Acuity ; Cancer ; Eye diseases ; Laboratory Medicine ; Medicine ; Medicine & Public Health ; Ophthalmology ; Optic nerve ; Patients ; Pharmaceutical Sciences/Technology ; Risk factors ; Surgery ; Surgical Oncology ; Tumors ; Vision ; Visual impairment</subject><ispartof>Eye (London), 2021-09, Vol.35 (9), p.2535-2542</ispartof><rights>The Author(s), under exclusive licence to The Royal College of Ophthalmologists 2020</rights><rights>The Author(s), under exclusive licence to The Royal College of Ophthalmologists 2020.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c451t-dc8525b4a33900ebf8e6cd15eee3be421c12f6558a77f49ff25a1a4d01a3ac713</citedby><cites>FETCH-LOGICAL-c451t-dc8525b4a33900ebf8e6cd15eee3be421c12f6558a77f49ff25a1a4d01a3ac713</cites><orcidid>0000-0002-2588-5533 ; 0000-0001-6377-0254</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377043/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377043/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,41467,42536,51297,53769,53771</link.rule.ids></links><search><creatorcontrib>Jian, Tianming</creatorcontrib><creatorcontrib>Sun, Fengyuan</creatorcontrib><creatorcontrib>Wu, Tong</creatorcontrib><creatorcontrib>Zhao, Liang</creatorcontrib><creatorcontrib>Huang, Xiaoming</creatorcontrib><creatorcontrib>Wang, Lina</creatorcontrib><creatorcontrib>He, Yanjin</creatorcontrib><creatorcontrib>Tang, Dongrun</creatorcontrib><title>Postoperative severe visual impairment: surgical outcome of 165 patients with orbital tumours in the muscle cone</title><title>Eye (London)</title><addtitle>Eye</addtitle><description>Objective
This study aimed to evaluate the risk factors of postoperative severe vision impairment (PSVI) for a primary orbital tumour in the muscle cone.
Methods
A retrospective analysis of the patients who underwent orbitotomy for primary intraconal tumours at the Tianjin Medical University Eye Hospital from January 2010 to December 2015.
Results
A total of 165 cases of orbitotomy for primary orbital tumours in the muscle cone were included in the study. Postoperatively, 12 cases with vision acuity ≤20/400 or ≥4 rows of vision decline and without any corrected effect were analysed as PSVI, including no light perception (NLP) for 3 cases. The multivariate logistic regression indicated that the tumour in orbital apex (
P
= 0.048, OR = 4.912, 95% CI: 1.011–23.866), severe optic nerve displacement (
P
= 0.030, OR = 6.007, 95% CI: 1.184–30.473) and intraoperative tight adhesion (
P
= 0.003, OR = 12.031, 95% CI: 2.282–63.441) were the independent risk factors for PSVI.
Conclusions
The incidence of PSVI for the intraconal tumour was 7.3%, and the incidence of NLP was 1.8%. The tumour in orbital apex, severe optic nerve displacement and intraoperative tight adhesion were independent risk factors for PSVI.</description><subject>692/499</subject><subject>692/699/3161/3178</subject><subject>692/700/565/545</subject><subject>Acuity</subject><subject>Cancer</subject><subject>Eye diseases</subject><subject>Laboratory Medicine</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Ophthalmology</subject><subject>Optic nerve</subject><subject>Patients</subject><subject>Pharmaceutical Sciences/Technology</subject><subject>Risk factors</subject><subject>Surgery</subject><subject>Surgical Oncology</subject><subject>Tumors</subject><subject>Vision</subject><subject>Visual impairment</subject><issn>0950-222X</issn><issn>1476-5454</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kUtr3DAUhUVpaKbT_oGuBNl040Zv2V0EQugjEEgWKXQnZM31jIJtuXpMyb-P0gkN7SIrge53Dufeg9AHSj5RwtvTJKjgvCGMNIQyTRr9Cq2o0KqRQorXaEU6SRrG2M9j9DalO0LqUJM36Jhz2grRkRVabkLKYYFos98DTrCHCHjvU7Ej9tNifZxgzp9xKnHrXf0MJbswAQ4DpkripQorkPBvn3c4xN7nCuUyhRIT9jPOO8BTSW4E7MIM79DRYMcE75_eNfrx9cvtxffm6vrb5cX5VeOEpLnZuFYy2QvLeUcI9EMLym2oBADeg2DUUTYoKVur9SC6YWDSUis2hFpunaZ8jc4OvkvpJ9i4mjHa0SzRTzbem2C9-Xcy-53Zhr1peb1RvesafXwyiOFXgZTN5JODcbQzhJIME4popTslK3ryH3pXt5_reoZJxZToWPeYiB0oF0NKEYa_YSgxj4WaQ6GmFmr-FGp0FfGDKFV43kJ8tn5B9QBx_KSA</recordid><startdate>20210901</startdate><enddate>20210901</enddate><creator>Jian, Tianming</creator><creator>Sun, Fengyuan</creator><creator>Wu, Tong</creator><creator>Zhao, Liang</creator><creator>Huang, Xiaoming</creator><creator>Wang, Lina</creator><creator>He, Yanjin</creator><creator>Tang, Dongrun</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-2588-5533</orcidid><orcidid>https://orcid.org/0000-0001-6377-0254</orcidid></search><sort><creationdate>20210901</creationdate><title>Postoperative severe visual impairment: surgical outcome of 165 patients with orbital tumours in the muscle cone</title><author>Jian, Tianming ; Sun, Fengyuan ; Wu, Tong ; Zhao, Liang ; Huang, Xiaoming ; Wang, Lina ; He, Yanjin ; Tang, Dongrun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c451t-dc8525b4a33900ebf8e6cd15eee3be421c12f6558a77f49ff25a1a4d01a3ac713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>692/499</topic><topic>692/699/3161/3178</topic><topic>692/700/565/545</topic><topic>Acuity</topic><topic>Cancer</topic><topic>Eye diseases</topic><topic>Laboratory Medicine</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Ophthalmology</topic><topic>Optic nerve</topic><topic>Patients</topic><topic>Pharmaceutical Sciences/Technology</topic><topic>Risk factors</topic><topic>Surgery</topic><topic>Surgical Oncology</topic><topic>Tumors</topic><topic>Vision</topic><topic>Visual impairment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jian, Tianming</creatorcontrib><creatorcontrib>Sun, Fengyuan</creatorcontrib><creatorcontrib>Wu, Tong</creatorcontrib><creatorcontrib>Zhao, Liang</creatorcontrib><creatorcontrib>Huang, Xiaoming</creatorcontrib><creatorcontrib>Wang, Lina</creatorcontrib><creatorcontrib>He, Yanjin</creatorcontrib><creatorcontrib>Tang, Dongrun</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Eye (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jian, Tianming</au><au>Sun, Fengyuan</au><au>Wu, Tong</au><au>Zhao, Liang</au><au>Huang, Xiaoming</au><au>Wang, Lina</au><au>He, Yanjin</au><au>Tang, Dongrun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Postoperative severe visual impairment: surgical outcome of 165 patients with orbital tumours in the muscle cone</atitle><jtitle>Eye (London)</jtitle><stitle>Eye</stitle><date>2021-09-01</date><risdate>2021</risdate><volume>35</volume><issue>9</issue><spage>2535</spage><epage>2542</epage><pages>2535-2542</pages><issn>0950-222X</issn><eissn>1476-5454</eissn><abstract>Objective
This study aimed to evaluate the risk factors of postoperative severe vision impairment (PSVI) for a primary orbital tumour in the muscle cone.
Methods
A retrospective analysis of the patients who underwent orbitotomy for primary intraconal tumours at the Tianjin Medical University Eye Hospital from January 2010 to December 2015.
Results
A total of 165 cases of orbitotomy for primary orbital tumours in the muscle cone were included in the study. Postoperatively, 12 cases with vision acuity ≤20/400 or ≥4 rows of vision decline and without any corrected effect were analysed as PSVI, including no light perception (NLP) for 3 cases. The multivariate logistic regression indicated that the tumour in orbital apex (
P
= 0.048, OR = 4.912, 95% CI: 1.011–23.866), severe optic nerve displacement (
P
= 0.030, OR = 6.007, 95% CI: 1.184–30.473) and intraoperative tight adhesion (
P
= 0.003, OR = 12.031, 95% CI: 2.282–63.441) were the independent risk factors for PSVI.
Conclusions
The incidence of PSVI for the intraconal tumour was 7.3%, and the incidence of NLP was 1.8%. The tumour in orbital apex, severe optic nerve displacement and intraoperative tight adhesion were independent risk factors for PSVI.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>33184490</pmid><doi>10.1038/s41433-020-01270-7</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-2588-5533</orcidid><orcidid>https://orcid.org/0000-0001-6377-0254</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0950-222X |
| ispartof | Eye (London), 2021-09, Vol.35 (9), p.2535-2542 |
| issn | 0950-222X 1476-5454 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8377043 |
| source | Springer Nature - Complete Springer Journals; PubMed Central |
| subjects | 692/499 692/699/3161/3178 692/700/565/545 Acuity Cancer Eye diseases Laboratory Medicine Medicine Medicine & Public Health Ophthalmology Optic nerve Patients Pharmaceutical Sciences/Technology Risk factors Surgery Surgical Oncology Tumors Vision Visual impairment |
| title | Postoperative severe visual impairment: surgical outcome of 165 patients with orbital tumours in the muscle cone |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T12%3A53%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Postoperative%20severe%20visual%20impairment:%20surgical%20outcome%20of%20165%20patients%20with%20orbital%20tumours%20in%20the%20muscle%20cone&rft.jtitle=Eye%20(London)&rft.au=Jian,%20Tianming&rft.date=2021-09-01&rft.volume=35&rft.issue=9&rft.spage=2535&rft.epage=2542&rft.pages=2535-2542&rft.issn=0950-222X&rft.eissn=1476-5454&rft_id=info:doi/10.1038/s41433-020-01270-7&rft_dat=%3Cproquest_pubme%3E2562649291%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2562649291&rft_id=info:pmid/33184490&rfr_iscdi=true |