Long-read whole-genome methylation patterning using enzymatic base conversion and nanopore sequencing

Abstract Long-read whole-genome sequencing analysis of DNA methylation would provide useful information on the chromosomal context of gene expression regulation. Here we describe the development of a method that improves the read length generated by using the bisulfite-sequencing-based approach. In...

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Veröffentlicht in:Nucleic acids research 2021-08, Vol.49 (14), p.e81-e81
Hauptverfasser: Sakamoto, Yoshitaka, Zaha, Suzuko, Nagasawa, Satoi, Miyake, Shuhei, Kojima, Yasuyuki, Suzuki, Ayako, Suzuki, Yutaka, Seki, Masahide
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Sprache:eng
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