Dynamic Patterns of N6-Methyladenosine Profiles of Messenger RNA Correlated with the Cardiomyocyte Regenerability during the Early Heart Development in Mice

N6-Methyladenosine (m6A) plays important roles in regulating mRNA processing. Despite rapid progress in this field, little is known about the role and mechanism of m6A modification in myocardial development and cardiomyocyte regeneration. Existing studies have shown that the heart tissues of newborn...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2021, Vol.2021 (1), p.5537804-5537804
Hauptverfasser:	Yang, Yuhui, Shen, Siman, Cai, Yin, Zeng, Kejun, Liu, Keyu, Li, Simeng, Zeng, Lanfen, Chen, Linming, Tang, Jing, Hu, Zhe, Xia, Zhengyuan, Zhang, Liangqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - analogs & derivatives Adenosine - chemistry Animals Cardiomyocytes Cell cycle Disease Enzymes Gene Expression Regulation, Developmental Genes Heart - embryology Heart - physiology Laboratory animals Male Mammals Mice Mice, Inbred C57BL Myocytes, Cardiac - cytology Myocytes, Cardiac - metabolism RNA, Messenger - chemistry RNA, Messenger - genetics RNA, Messenger - metabolism Signal transduction Stem cells
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