Therapeutic Effect of Murine Bone Marrow-Derived Mesenchymal Stromal/Stem Cells and Human Placental Extract on Testicular Toxicity Resulting from Doxorubicin in Rats

Oncotherapeutics like doxorubicin can affect male gonads; as a result, it leads to infertility. This work was conducted to demonstrate the toxic effects of doxorubicin on testes of male albino rats. Fifty male albino rats aged 5-7 weeks were used in this study. The animals were randomly separated in...

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Veröffentlicht in:	BioMed research international 2021, Vol.2021 (1), p.9979670-9979670
Hauptverfasser:	AbdRabou, Mervat Ahmed, Mehany, Ahmed B. M., Farrag, Islam M., Belal, Amany, Abdelzaher, Othman F., El-Sharkawy, Abdou, Abd El-Azez, Asmaa M., EL-Sharkawy, Salah M., Al Badawi, Manal H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adverse and side effects Antioxidants Apoptosis Bone marrow Bone marrow cells Cancer Cancer therapies Care and treatment Cell cycle Cell division Cellular therapy Chemical properties Chemotherapy Complications and side effects Connective tissue cells Cytokines Doxorubicin Drugs Enzymes Flow cytometry Follicle-stimulating hormone Gonads Growth factors Health aspects Hematopoietic stem cells Infertility Intoxication Laboratory animals Lipid peroxidation Luteinizing hormone Males Mesenchyme Oxidative stress Placenta Sperm Spermatogenesis Stem cell transplantation Stem cells Stromal cells Testes Testosterone Therapeutics, Experimental Toxicity Transplantation Tubules Tumors
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