Serotonin 5‐HT7 receptors require cyclin‐dependent kinase 5 to rescue hippocampal synaptic plasticity in a mouse model of Fragile X Syndrome

Fragile X Syndrome is a genetic form of intellectual disability associated with autism, epilepsy and mood disorders. Electrophysiology studies in Fmr1 knockout (KO) mice, a murine model of Fragile X Syndrome, have demonstrated alterations of synaptic plasticity, with exaggerated long‐term depression...

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Veröffentlicht in:The European journal of neuroscience 2021-07, Vol.54 (1), p.4124-4132
Hauptverfasser: Costa, Lara, Tempio, Alessandra, Lacivita, Enza, Leopoldo, Marcello, Ciranna, Lucia
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Sprache:eng
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