Aloperine protects against cerebral ischemia/reperfusion injury via activating the PI3K/AKT signaling pathway in rats

Cerebral ischemia is among the leading causes of death and long-term disability worldwide. The aim of the present study was to investigate the effects of aloperine (ALO) on cerebral ischemia/reperfusion (I/R) injury in rats and elucidate the possible underlying mechanisms. Therefore, a rat model of...

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Veröffentlicht in:	Experimental and therapeutic medicine 2021-10, Vol.22 (4), Article 1045
Hauptverfasser:	Li, Zhimin, Cao, Xing, Xiao, Ligen, Zhou, Ruijiao
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids Alzheimer's disease Antioxidants Apoptosis Beans Biotechnology Blood-brain barrier Brain Care and treatment Carotid arteries Cerebral ischemia Chemical properties Chinese medicine Development and progression Drug dosages Embolisms Ethanol Health aspects Inflammation Ischemia Laboratory animals Legumes Mimosaceae Oxidative stress Physiological aspects Protein kinases Reactive oxygen species Reperfusion injury Stroke Surgery Veins & arteries
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