Procaine–The Controversial Geroprotector Candidate: New Insights Regarding Its Molecular and Cellular Effects

Since its discovery in 1905 and its employment in everyday medical practice as a local anesthetic, to its highly controversial endorsement as an “anti-aging” molecule in the sixties and seventies, procaine is part of the history of medicine and gerontoprophylaxis. Procaine can be considered a “veter...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2021, Vol.2021 (1), p.3617042
Hauptverfasser:	Gradinaru, Daniela, Ungurianu, Anca, Margina, Denisa, Moreno-Villanueva, Maria, Bürkle, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aging Aging - drug effects Anesthetics, Local - adverse effects Anesthetics, Local - pharmacology Animals Antioxidants Antioxidants - adverse effects Antioxidants - pharmacology Biosynthesis Clinical medicine Cocaine DNA methylation Drug dosages Epigenesis, Genetic - drug effects Free radicals Humans Hypotheses Medical research Metabolism Metabolites Pharmacodynamics Pharmacokinetics Procaine - adverse effects Procaine - pharmacology Review
Online-Zugang:	Volltext
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