Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms

We describe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell responses, soluble markers of inflammation, and antibody levels and neutralization capacity longitudinally in 70 individuals with PCR-confirmed SARS-CoV-2 infection. Participants represent a spectrum of illness...

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Veröffentlicht in:	Cell reports (Cambridge) 2021-08, Vol.36 (6), p.109518-109518, Article 109518
Hauptverfasser:	Peluso, Michael J., Deitchman, Amelia N., Torres, Leonel, Iyer, Nikita S., Munter, Sadie E., Nixon, Christopher C., Donatelli, Joanna, Thanh, Cassandra, Takahashi, Saki, Hakim, Jill, Turcios, Keirstinne, Janson, Owen, Hoh, Rebecca, Tai, Viva, Hernandez, Yanel, Fehrman, Emily A., Spinelli, Matthew A., Gandhi, Monica, Trinh, Lan, Wrin, Terri, Petropoulos, Christos J., Aweeka, Francesca T., Rodriguez-Barraquer, Isabel, Kelly, J. Daniel, Martin, Jeffrey N., Deeks, Steven G., Greenhouse, Bryan, Rutishauser, Rachel L., Henrich, Timothy J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies, Neutralizing - immunology Antibodies, Viral - immunology CD8-Positive T-Lymphocytes - immunology COVID-19 COVID-19 - complications COVID-19 - immunology COVID-19 - pathology Disease Progression Female Humans immunity long COVID Male Middle Aged PASC post-acute sequelae of SARS-CoV-2 infection SARS-CoV-2 SARS-CoV-2 - immunology Severity of Illness Index T cell Virus Shedding - immunology
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